Details of the Target

General Information of Target

Target ID LDTP08645
Target Name Coiled-coil domain-containing protein 13 (CCDC13)
Gene Name CCDC13
Gene ID 152206
Synonyms
Coiled-coil domain-containing protein 13
3D Structure
Download
2D Sequence (FASTA)
Download
3D Structure (PDB)
Download
Sequence
MAADESSQNTLRLQFKAMQEMQHKRLQKQMEKKREKELSLKSRADDQEEPLEVSDGLSLL
HAGEPNSKNSFEKRVLEDEIEHLRNELRETVDENGRLYKLLKERDFEIKHLKKKIEEDRF
AFTGTAGVAGDVVATKIVELSKKNRLLMAESEGAKTRVKQLTNRIQELERELQTALTRLS
AKGATDAGAKPPRAQMGDRALLETPEVKALQDRLVATNLKMSDLRNQIQSVKQELRMAQK
VLAREVGEDINVQQLLSSPGTWRGRAQQILVLQSKVQELEKQLGQARSQSAGTASDELSV
YPDPRKLSAQEKNLLRIRSLEREKQEGLEKLASERDVLQRELEELKKKFEGMRSRNKLLS
SEMKTLKSQMGTLVEKGRHDDELIDALMDQLKQLQEILGSLSLQEEKTRVSQHHLDQQLN
SEAQRSNSLVAQLQAMVAEREAKVRQLEMEIGQLNVHYLRNKGVGEGSSGREVSPAYTQF
LEDPGLTKSPASAGDHVGRLGSSRSVTSLGHTLVESALTRPSLPSPHRTSPRFSDSPEQK
GWQAQVSEIKALWQAAEVERDRLTEFVTVLQKRVEESNSKLLESERKLQEERHRTVVLEQ
HLEKIRLEPGKASASQRAAPRTKTGLPTSNNRHNPTGSEKKDPSFAQLSDVPVESQMEEL
TTRLAIQVEENEMLKAALGSALRGKEEDFRMYHEILGQVKSVFLQALRQQKTGKQ
Target Bioclass
Other
Subcellular location
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriolar satellite
Function Required for primary cilia formation and promotes the localization of the ciliopathy protein BBS4 to both centriolar satellites and cilia.
Uniprot ID
Q8IYE1
Ensemble ID
ENST00000310232.11
HGNC ID
HGNC:26358

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
ATP probe
 Probe Info  		N.A.  LDD0199  [1]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 7 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Peroxisomal bifunctional enzyme (EHHADH) Enoyl-CoA hydratase/isomerase family; 3-hydroxyacyl-CoA dehydrogenase family Q08426
Ubiquitin thioesterase ZRANB1 (ZRANB1) Peptidase C64 family Q9UGI0
E3 ubiquitin-protein ligase TRIM23 (TRIM23) Arf family P36406
TNF receptor-associated factor 3 (TRAF3) TNF receptor-associated factor family Q13114
E3 SUMO-protein ligase ZBED1 (ZBED1) . O96006
Germ cell-less protein-like 1 (GMCL1) . Q96IK5
RalA-binding protein 1 (RALBP1) . Q15311
Transporter and channel
Click To Hide/Show 2 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Leucine zipper putative tumor suppressor 1 (LZTS1) LZTS family Q9Y250
Optineurin (OPTN) . Q96CV9
Transcription factor
Click To Hide/Show 4 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Zinc finger and BTB domain-containing protein 22 (ZBTB22) Krueppel C2H2-type zinc-finger protein family O15209
Zinc finger and BTB domain-containing protein 43 (ZBTB43) Krueppel C2H2-type zinc-finger protein family O43298
Zinc finger protein 670 (ZNF670) Krueppel C2H2-type zinc-finger protein family Q9BS34
Myogenic factor 5 (MYF5) . P13349
Other
Click To Hide/Show 24 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Ankyrin repeat and SOCS box protein 15 (ASB15) Ankyrin SOCS box (ASB) family Q8WXK1
Cerebellar degeneration-related protein 2 (CDR2) CDR2 family Q01850
G1/S-specific cyclin-D3 (CCND3) Cyclin family P30281
Protein FAM161A (FAM161A) FAM161 family Q3B820
Protein FAM161B (FAM161B) FAM161 family Q96MY7
Protein FAM221B (FAM221B) FAM221 family A6H8Z2
Protein FAM90A1 (FAM90A1) FAM90 family Q86YD7
Golgin subfamily A member 2 (GOLGA2) GOLGA2 family Q08379
Keratin, type I cuticular Ha4 (KRT34) Intermediate filament family O76011
Neurofilament light polypeptide (NEFL) Intermediate filament family P07196
Beta-taxilin (TXLNB) Taxilin family Q8N3L3
Trichoplein keratin filament-binding protein (TCHP) TCHP family Q9BT92
T-cell leukemia/lymphoma protein 1A (TCL1A) TCL1 family P56279
Tuftelin-interacting protein 11 (TFIP11) TFP11/STIP family Q9UBB9
Small ribosomal subunit protein uS2 (RPSA) Universal ribosomal protein uS2 family P08865
Vacuolar protein sorting-associated protein 52 homolog (VPS52) VPS52 family Q8N1B4
Coiled-coil domain-containing protein 120 (CCDC120) . Q96HB5
EF-hand domain-containing family member C2 (EFHC2) . Q5JST6
Enkurin domain-containing protein 1 (ENKD1) . Q9H0I2
Heat shock factor 2-binding protein (HSF2BP) . O75031
Huntingtin-associated protein 1 (HAP1) . P54257
Microspherule protein 1 (MCRS1) . Q96EZ8
Protein hinderin (KIAA1328) . Q86T90
Testis-specific protein 10-interacting protein (TSGA10IP) . Q3SY00

References

1 Targeted Proteomic Approaches for Proteome-Wide Characterizations of the AMP-Binding Capacities of Kinases. J Proteome Res. 2022 Aug 5;21(8):2063-2070. doi: 10.1021/acs.jproteome.2c00225. Epub 2022 Jul 12.