Details of the Target
General Information of Target
| Target ID | LDTP08513 | |||||
|---|---|---|---|---|---|---|
| Target Name | Glycerate kinase (GLYCTK) | |||||
| Gene Name | GLYCTK | |||||
| Gene ID | 132158 | |||||
| Synonyms |
HBEBP4; Glycerate kinase; EC 2.7.1.31; HBeAg-binding protein 4 |
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| 3D Structure | ||||||
| Sequence |
MAAALQVLPRLARAPLHPLLWRGSVARLASSMALAEQARQLFESAVGAVLPGPMLHRALS
LDPGGRQLKVRDRNFQLRQNLYLVGFGKAVLGMAAAAEELLGQHLVQGVISVPKGIRAAM ERAGKQEMLLKPHSRVQVFEGAEDNLPDRDALRAALAIQQLAEGLTADDLLLVLISGGGS ALLPAPIPPVTLEEKQTLTRLLAARGATIQELNTIRKALSQLKGGGLAQAAYPAQVVSLI LSDVVGDPVEVIASGPTVASSHNVQDCLHILNRYGLRAALPRSVKTVLSRADSDPHGPHT CGHVLNVIIGSNVLALAEAQRQAEALGYQAVVLSAAMQGDVKSMAQFYGLLAHVARTRLT PSMAGASVEEDAQLHELAAELQIPDLQLEEALETMAWGRGPVCLLAGGEPTVQLQGSGRG GRNQELALRVGAELRRWPLGPIDVLFLSGGTDGQDGPTEAAGAWVTPELASQAAAEGLDI ATFLAHNDSHTFFCCLQGGAHLLHTGMTGTNVMDTHLLFLRPR |
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| Target Bioclass |
Enzyme
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| Family |
Glycerate kinase type-2 family
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| Subcellular location |
Cytoplasm
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| Uniprot ID | ||||||
| Ensemble ID | ||||||
| HGNC ID | ||||||
Target Site Mutations in Different Cell Lines
| Cell line | Mutation details | Probe for labeling this protein in this cell | |||
|---|---|---|---|---|---|
| Ishikawa (Heraklio) 02 ER | Deletion: p.S343VfsTer92 | DBIA Probe Info | |||
| LNCaP clone FGC | SNV: p.A379S | . | |||
| MOLT4 | SNV: p.E127K; p.A278V | . | |||
| NCIH1155 | SNV: p.A432V | . | |||
| TOV21G | SNV: p.R27S | . | |||
Probe(s) Labeling This Target
ABPP Probe
| Probe name | Structure | Binding Site(Ratio) | Interaction ID | Ref | |
|---|---|---|---|---|---|
|
DBIA Probe Info |
 |
C67(1.87) | LDD3424 | [1] | |
Competitor(s) Related to This Target