Details of the Target
General Information of Target
| Target ID | LDTP08481 | |||||
|---|---|---|---|---|---|---|
| Target Name | UNC5C-like protein (UNC5CL) | |||||
| Gene Name | UNC5CL | |||||
| Gene ID | 222643 | |||||
| Synonyms |
ZUD; UNC5C-like protein; Protein unc-5 homolog C-like; ZU5 and death domain-containing protein |
|||||
| 3D Structure | ||||||
| Sequence |
MCPQESSFQPSQFLLLVGVPVASVLLLAQCLRWHCPRRLLGACWTLNGQEEPVSQPTPQL
ENEVSRQHLPATLPEMVAFYQELHTPTQGQTMVRQLMHKLLVFSAREVDHRGGCLMLQDT GISLLIPPGAVAVGRQERVSLILVWDLSDAPSLSQAQGLVSPVVACGPHGASFLKPCTLT FKHCAEQPSHARTYSSNTTLLDAKVWRPLGRPGAHASRDECRIHLSHFSLYTCVLEAPVG REARKWLQLAVFCSPLVPGQSHLQLRIYFLNNTPCALQWALTNEQPHGGRLRGPCQLFDF NGARGDQCLKLTYISEGWENVDDSSCQLVPHLHIWHGKCPFRSFCFRRKAADENEDCSAL TNEIIVTMHTFQDGLETKYMEILRFQASEEESWAAPPPVSQPPPCNRLPPELFEQLRMLL EPNSITGNDWRRLASHLGLCGMKIRFLSCQRSPAAAILELFEEQNGSLQELHYLMTVMER LDCASAIQNYLSGTHGGSPGPERGGARDNQGLELDEKL |
|||||
| Target Bioclass |
Other
|
|||||
| Family |
Unc-5 family
|
|||||
| Subcellular location |
Membrane
|
|||||
| Function | Inhibits NF-kappa-B-dependent transcription by impairing NF-kappa-B binding to its targets. | |||||
| Uniprot ID | ||||||
| Ensemble ID | ||||||
| HGNC ID | ||||||
Probe(s) Labeling This Target
ABPP Probe
| Probe name | Structure | Binding Site(Ratio) | Interaction ID | Ref | |
|---|---|---|---|---|---|
|
DBIA Probe Info |
 |
C184(1.85) | LDD3314 | [1] | |
|
NAIA_5 Probe Info |
 |
N.A. | LDD2225 | [2] | |
Competitor(s) Related to This Target
References