Details of the Target
General Information of Target
| Target ID | LDTP08472 | |||||
|---|---|---|---|---|---|---|
| Target Name | Epidermal growth factor-like protein 6 (EGFL6) | |||||
| Gene Name | EGFL6 | |||||
| Gene ID | 25975 | |||||
| Synonyms |
MAEG; Epidermal growth factor-like protein 6; EGF-like protein 6; MAM and EGF domains-containing gene protein |
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| 3D Structure | ||||||
| Sequence |
MPLPWSLALPLLLSWVAGGFGNAASARHHGLLASARQPGVCHYGTKLACCYGWRRNSKGV
CEATCEPGCKFGECVGPNKCRCFPGYTGKTCSQDVNECGMKPRPCQHRCVNTHGSYKCFC LSGHMLMPDATCVNSRTCAMINCQYSCEDTEEGPQCLCPSSGLRLAPNGRDCLDIDECAS GKVICPYNRRCVNTFGSYYCKCHIGFELQYISGRYDCIDINECTMDSHTCSHHANCFNTQ GSFKCKCKQGYKGNGLRCSAIPENSVKEVLRAPGTIKDRIKKLLAHKNSMKKKAKIKNVT PEPTRTPTPKVNLQPFNYEEIVSRGGNSHGGKKGNEEKMKEGLEDEKREEKALKNDIEER SLRGDVFFPKVNEAGEFGLILVQRKALTSKLEHKDLNISVDCSFNHGICDWKQDREDDFD WNPADRDNAIGFYMAVPALAGHKKDIGRLKLLLPDLQPQSNFCLLFDYRLAGDKVGKLRV FVKNSNNALAWEKTTSEDEKWKTGKIQLYQGTDATKSIIFEAERGKGKTGEIAVDGVLLV SGLCPDSLLSVDD |
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| Target Type |
Literature-reported
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| Target Bioclass |
Other
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| Family |
Nephronectin family
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| Subcellular location |
Secreted, extracellular space, extracellular matrix, basement membrane
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| Function | May bind integrin alpha-8/beta-1 and play a role in hair follicle morphogenesis. Promotes matrix assembly. | |||||
| TTD ID | ||||||
| Uniprot ID | ||||||
| DrugMap ID | ||||||
| Ensemble ID | ||||||
| HGNC ID | ||||||
Target Site Mutations in Different Cell Lines
Probe(s) Labeling This Target
ABPP Probe
| Probe name | Structure | Binding Site(Ratio) | Interaction ID | Ref | |
|---|---|---|---|---|---|
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IA-alkyne Probe Info |
 |
N.A. | LDD0165 | [1] | |
The Interaction Atlas With This Target