Details of the Target
General Information of Target
| Target ID | LDTP08341 | |||||
|---|---|---|---|---|---|---|
| Target Name | Probable D-lactate dehydrogenase, mitochondrial (LDHD) | |||||
| Gene Name | LDHD | |||||
| Gene ID | 197257 | |||||
| Synonyms |
Probable D-lactate dehydrogenase, mitochondrial; DLD; Lactate dehydrogenase D; EC 1.1.2.4 |
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| 3D Structure | ||||||
| Sequence |
MARLLRSATWELFPWRGYCSQKAKGELCRDFVEALKAVVGGSHVSTAAVVREQHGRDESV
HRCEPPDAVVWPQNVEQVSRLAALCYRQGVPIIPFGTGTGLEGGVCAVQGGVCVNLTHMD RILELNQEDFSVVVEPGVTRKALNAHLRDSGLWFPVDPGADASLCGMAATGASGTNAVRY GTMRDNVLNLEVVLPDGRLLHTAGRGRHFRFGFWPEIPHHTAWYSPCVSLGRRKSAAGYN LTGLFVGSEGTLGLITATTLRLHPAPEATVAATCAFPSVQAAVDSTVHILQAAVPVARIE FLDEVMMDACNRYSKLNCLVAPTLFLEFHGSQQALEEQLQRTEEIVQQNGASDFSWAKEA EERSRLWTARHNAWYAALATRPGCKGYSTDVCVPISRLPEIVVQTKEDLNASGLTGSIVG HVGDGNFHCILLVNPDDAEELGRVKAFAEQLGRRALALHGTCTGEHGIGMGKRQLLQEEV GAVGVETMRQLKAVLDPQGLMNPGKVL |
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| Target Bioclass |
Enzyme
|
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| Family |
FAD-binding oxidoreductase/transferase type 4 family
|
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| Subcellular location |
Mitochondrion
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| Function | Involved in D-lactate, but not L-lactate catabolic process. | |||||
| Uniprot ID | ||||||
| Ensemble ID | ||||||
| HGNC ID | ||||||
Probe(s) Labeling This Target
ABPP Probe
| Probe name | Structure | Binding Site(Ratio) | Interaction ID | Ref | |
|---|---|---|---|---|---|
|
DBIA Probe Info |
 |
C85(1.28) | LDD3325 | [1] | |
|
IPM Probe Info |
 |
N.A. | LDD0147 | [2] | |
|
TFBX Probe Info |
 |
N.A. | LDD0148 | [2] | |
|
Phosphinate-6 Probe Info |
 |
N.A. | LDD0018 | [3] | |
|
NAIA_5 Probe Info |
 |
C384(0.00); C274(0.00) | LDD2223 | [4] | |
Competitor(s) Related to This Target
References