General Information of Target

Target ID LDTP08167
Target Name Protein S100-A7A (S100A7A)
Gene Name S100A7A
Gene ID 338324
Synonyms
S100A15; S100A7L1; Protein S100-A7A; S100 calcium-binding protein A15; S100 calcium-binding protein A7-like 1; S100 calcium-binding protein A7A
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MSNTQAERSIIGMIDMFHKYTGRDGKIEKPSLLTMMKENFPNFLSACDKKGIHYLATVFE
KKDKNEDKKIDFSEFLSLLGDIAADYHKQSHGAAPCSGGSQ
Target Bioclass
Other
Family
S-100 family
Subcellular location
Cytoplasm
Function May be involved in epidermal differentiation and inflammation and might therefore be important for the pathogenesis of psoriasis and other diseases.
Uniprot ID
Q86SG5
Ensemble ID
ENST00000329256.2
HGNC ID
HGNC:21657

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info 
C47(2.75); C96(3.28)  LDD2268  [1]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0022  KB02 BRX211 C47(2.75); C96(3.28)  LDD2268  [1]
 LDCM0023  KB03 BRX211 C47(3.94); C96(2.22)  LDD2685  [1]
 LDCM0024  KB05 BRX211 C47(7.16); C96(2.63)  LDD3102  [1]

References

1 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840