Details of the Target
General Information of Target
| Target ID | LDTP08101 | |||||
|---|---|---|---|---|---|---|
| Target Name | Cytoplasmic polyadenylation element-binding protein 2 (CPEB2) | |||||
| Gene Name | CPEB2 | |||||
| Gene ID | 132864 | |||||
| Synonyms |
Cytoplasmic polyadenylation element-binding protein 2; CPE-BP2; CPE-binding protein 2; hCPEB-2 |
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| 3D Structure | ||||||
| Sequence |
MPPPSPDSENGFYPGLPSSMNPAFFPSFSPVSPHGCTGLSVPTSGGGGGGFGGPFSATAV
PPPPPPAMNIPQQQPPPPAAPQQPQSRRSPVSPQLQQQHQAAAAAFLQQRNSYNHHQPLL KQSPWSNHQSSGWGTGSMSWGAMHGRDHRRTGNMGIPGTMNQISPLKKPFSGNVIAPPKF TRSTPSLTPKSWIEDNVFRTDNNSNTLLPLQVRSSLQLPAWGSDSLQDSWCTAAGTSRID QDRSRMYDSLNMHSLENSLIDIMRAEHDPLKGRLSYPHPGTDNLLMLNGRSSLFPIDDGL LDDGHSDQVGVLNSPTCYSAHQNGERIERFSRKVFVGGLPPDIDEDEITASFRRFGPLVV DWPHKAESKSYFPPKGYAFLLFQEESSVQALIDACIEEDGKLYLCVSSPTIKDKPVQIRP WNLSDSDFVMDGSQPLDPRKTIFVGGVPRPLRAVELAMIMDRLYGGVCYAGIDTDPELKY PKGAGRVAFSNQQSYIAAISARFVQLQHGDIDKRVEVKPYVLDDQMCDECQGARCGGKFA PFFCANVTCLQYYCEFCWANIHSRAGREFHKPLVKEGADRPRQIHFRWN |
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| Target Bioclass |
Other
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| Family |
RRM CPEB family
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| Subcellular location |
Cytoplasm
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| Function |
May play a role in translational regulation of stored mRNAs in transcriptionally inactive haploid spermatids. Binds to poly(U) RNA oligomers. Required for cell cycle progression, specifically for the transition from metaphase to anaphase.
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| Uniprot ID | ||||||
| Ensemble ID | ||||||
| HGNC ID | ||||||
Probe(s) Labeling This Target
ABPP Probe
| Probe name | Structure | Binding Site(Ratio) | Interaction ID | Ref | |
|---|---|---|---|---|---|
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STPyne Probe Info |
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K513(7.48) | LDD0277 | [1] | |