Details of the Target

General Information of Target

Target ID LDTP08013
Target Name Ovochymase-2 (OVCH2)
Gene Name OVCH2
Synonyms
OVTN; Ovochymase-2; EC 3.4.21.-; Oviductin
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MLISRNKLILLLGIVFFERGKSATLSLPKAPSCGQSLVKVQPWNYFNIFSRILGGSQVEK
GSYPWQVSLKQRQKHICGGSIVSPQWVITAAHCIANRNIVSTLNVTAGEYDLSQTDPGEQ
TLTIETVIIHPHFSTKKPMDYDIALLKMAGAFQFGHFVGPICLPELREQFEAGFICTTAG
WGRLTEGGVLSQVLQEVNLPILTWEECVAALLTLKRPISGKTFLCTGFPDGGRDACQGDS
GGSLMCRNKKGAWTLAGVTSWGLGCGRGWRNNVRKSDQGSPGIFTDISKVLPWIHEHIQT
GNRRKSSRAWCSEQDVIVSGAEGKLHFPESLHLYYESKQRCVWTLLVPEEMHVLLSFSHL
DVESCHHSYLSMYSLEDRPIGKFCGESLPSSILIGSNSLRLKFVSDATDNAARFNLTYKA
LKPNYIPDSGCSYLTVLFEEGLIQSLNYPENYSDKANCDWIFQASKHHLIKLSFQSLEIE
ESGDCTSDYVTVHSDVERKKEIARLCGYDVPTPVLSPSSIMLISFHSDENGTCRGFQATV
SFIPKAGKKIELPTLWFPVLILVM
Target Bioclass
Enzyme
Family
Peptidase S1 family
Subcellular location
Secreted
Function May be required for sperm ADAM3 processing and consequential sperm fertilizing ability. In vitro, has an endopeptidase activity.
Uniprot ID
Q7RTZ1
HGNC ID
HGNC:29970

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
IPIAA_H
 Probe Info  		N.A.  LDD0030  [1]

References

1 SP3-Enabled Rapid and High Coverage Chemoproteomic Identification of Cell-State-Dependent Redox-Sensitive Cysteines. Mol Cell Proteomics. 2022 Apr;21(4):100218. doi: 10.1016/j.mcpro.2022.100218. Epub 2022 Feb 25.
Mass spectrometry data entry: PXD029500 , PXD031647