General Information of Target

Target ID LDTP07865
Target Name Regulator of hemoglobinization and erythroid cell expansion protein (RHEX)
Gene Name RHEX
Gene ID 440712
Synonyms
C1orf186; Regulator of hemoglobinization and erythroid cell expansion protein; Regulator of human erythroid cell expansion protein
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MLTEVMEVWHGLVIAVVSLFLQACFLTAINYLLSRHMAHKSEQILKAASLQVPRPSPGHH
HPPAVKEMKETQTERDIPMSDSLYRHDSDTPSDSLDSSCSSPPACQATEDVDYTQVVFSD
PGELKNDSPLDYENIKEITDYVNVNPERHKPSFWYFVNPALSEPAEYDQVAM
Target Bioclass
Other
Subcellular location
Cell membrane
Function Acts as a signaling transduction factor of the EPO-EPOR signaling pathway promoting erythroid cell differentiation.
Uniprot ID
Q6ZWK4
Ensemble ID
ENST00000331555.10
HGNC ID
HGNC:25341

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
NAIA_4
 Probe Info 
N.A.  LDD2226  [1]

References

1 N-Acryloylindole-alkyne (NAIA) enables imaging and profiling new ligandable cysteines and oxidized thiols by chemoproteomics. Nat Commun. 2023 Jun 15;14(1):3564. doi: 10.1038/s41467-023-39268-w.
Mass spectrometry data entry: PXD041264