Details of the Target

General Information of Target

Target ID LDTP07833
Target Name Solute carrier family 25 member 48 (SLC25A48)
Gene Name SLC25A48
Gene ID 153328
Synonyms
Solute carrier family 25 member 48
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MGSFQLEDFAAGWIGGAASVIVGHPLDTVKTRLQAGVGYGNTLSCIRVVYRRESMFGFFK
GMSFPLASIAVYNSVVFGVFSNTQRFLSQHRCGEPEASPPRTLSDLLLASMVAGVVSVGL
GGPVDLIKIRLQMQTQPFRDANLGLKSRAVAPAEQPAYQGPVHCITTIVRNEGLAGLYRG
ASAMLLRDVPGYCLYFIPYVFLSEWITPEACTGPSPCAVWLAGGMAGAISWGTATPMDVV
KSRLQADGVYLNKYKGVLDCISQSYQKEGLKVFFRGITVNAVRGFPMSAAMFLGYELSLQ
AIRGDHAVTSP
Target Bioclass
Transporter and channel
Family
Mitochondrial carrier (TC 2.A.29) family
Subcellular location
Mitochondrion inner membrane
Uniprot ID
Q6ZT89
Ensemble ID
ENST00000274513.9
HGNC ID
HGNC:30451

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
BT549 SNV: p.S230A .
C4II SNV: p.E172K .
EOL1 SNV: p.T207I .
HS936T SNV: p.P137S .
MFE319 SNV: p.R85W .
SUPT1 SNV: p.A289V .
TE4 SNV: p.R91C .

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
IPM
 Probe Info  		N.A.  LDD2156  [1]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 2 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Tensin-2 (TNS2) PTEN phosphatase protein family Q63HR2
Ubiquitin-associated and SH3 domain-containing protein B (UBASH3B) . Q8TF42
Other
Click To Hide/Show 5 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Cysteine-rich tail protein 1 (CYSRT1) CYSRT1 family A8MQ03
EGF-containing fibulin-like extracellular matrix protein 2 (EFEMP2) Fibulin family O95967
Keratin-associated protein 10-7 (KRTAP10-7) KRTAP type 10 family P60409
Paraneoplastic antigen Ma1 (PNMA1) PNMA family Q8ND90
TNF receptor-associated factor 1 (TRAF1) . Q13077

References

1 Benchmarking Cleavable Biotin Tags for Peptide-Centric Chemoproteomics. J Proteome Res. 2022 May 6;21(5):1349-1358. doi: 10.1021/acs.jproteome.2c00174. Epub 2022 Apr 25.
Mass spectrometry data entry: PXD031019