Details of the Target

General Information of Target

Target ID LDTP07788
Target Name Zinc finger protein ZFP2 (ZFP2)
Gene Name ZFP2
Gene ID 80108
Synonyms
ZNF751; Zinc finger protein ZFP2; Zfp-2; Zinc finger protein 751
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MEREGIWHSTLGETWEPNNWLEGQQDSHLSQVGVTHKETFTEMRVCGGNEFERCSSQDSI
LDTQQSIPMVKRPHNCNSHGEDATQNSELIKTQRMFVGKKIYECNQCSKTFSQSSSLLKH
QRIHTGEKPYKCNVCGKHFIERSSLTVHQRIHTGEKPYKCNECGKAFSQSMNLTVHQRTH
TGEKPYQCKECGKAFHKNSSLIQHERIHTGEKPYKCNECGKAFTQSMNLTVHQRTHTGEK
PYECNECGKAFSQSMHLIVHQRSHTGEKPYECSQCGKAFSKSSTLTLHQRNHTGEKPYKC
NKCGKSFSQSTYLIEHQRLHSGVKPFECNECGKAFSKNSSLTQHRRIHTGEKPYECMVCG
KHFTGRSSLTVHQVIHTGEKPYECNECGKAFSQSAYLIEHQRIHTGEKPYECDQCGKAFI
KNSSLTVHQRTHTGEKPYQCNECGKAFSRSTNLTRHQRTHT
Target Bioclass
Transcription factor
Family
Krueppel C2H2-type zinc-finger protein family
Subcellular location
Nucleus
Function Probable transcription factor involved in neuronal differentiation and/or phenotypic maintenance.
Uniprot ID
Q6ZN57
Ensemble ID
ENST00000361362.7
HGNC ID
HGNC:26138

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 2 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
IA-alkyne
 Probe Info  		N.A.  LDD0167  [1]
HHS-465
 Probe Info  		K128(0.00); K131(0.00); Y130(0.00)  LDD2240  [2]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 2 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
RNA 5'-monophosphate methyltransferase (BCDIN3D) Methyltransferase superfamily Q7Z5W3
E3 ubiquitin-protein ligase TRIM41 (TRIM41) TRIM/RBCC family Q8WV44
Transporter and channel
Click To Hide/Show 2 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Huntingtin (HTT) Huntingtin family P42858
Importin-8 (IPO8) Importin beta family O15397
Other
Click To Hide/Show 6 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Golgin subfamily A member 2 (GOLGA2) GOLGA2 family Q08379
Keratin, type I cytoskeletal 40 (KRT40) Intermediate filament family Q6A162
Prelamin-A/C (LMNA) Intermediate filament family P02545
Microtubule-associated tumor suppressor candidate 2 (MTUS2) MTUS1 family Q5JR59
PRKCA-binding protein (PICK1) . Q9NRD5
Sprouty-related, EVH1 domain-containing protein 1 (SPRED1) . Q7Z699

References

1 SP3-FAIMS Chemoproteomics for High-Coverage Profiling of the Human Cysteinome*. Chembiochem. 2021 May 14;22(10):1841-1851. doi: 10.1002/cbic.202000870. Epub 2021 Feb 18.
Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060
2 Global profiling identifies a stress-responsive tyrosine site on EDC3 regulating biomolecular condensate formation. Cell Chem Biol. 2022 Dec 15;29(12):1709-1720.e7. doi: 10.1016/j.chembiol.2022.11.008. Epub 2022 Dec 6.
Mass spectrometry data entry: PXD038010