Details of the Target
General Information of Target
| Target ID | LDTP07685 | |||||
|---|---|---|---|---|---|---|
| Target Name | Serine protease 57 (PRSS57) | |||||
| Gene Name | PRSS57 | |||||
| Gene ID | 400668 | |||||
| Synonyms |
PRSSL1; Serine protease 57; EC 3.4.21.-; Neutrophil serine protease 4; NSP4; Serine protease 1-like protein 1 |
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| 3D Structure | ||||||
| Sequence |
MGLGLRGWGRPLLTVATALMLPVKPPAGSWGAQIIGGHEVTPHSRPYMASVRFGGQHHCG
GFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVLSTAEPTQQVFGIDALTTHPDYHPMTHA NDICLLRLNGSAVLGPAVGLLRPPGRRARPPTAGTRCRVAGWGFVSDFEELPPGLMEAKV RVLDPDVCNSSWKGHLTLTMLCTRSGDSHRRGFCSADSGGPLVCRNRAHGLVSFSGLWCG DPKTPDVYTQVSAFVAWIWDVVRRSSPQPGPLPGTTRPPGEAA |
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| Target Bioclass |
Enzyme
|
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| Family |
Peptidase S1 family
|
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| Subcellular location |
Cytoplasmic granule lumen
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| Function | Serine protease that cleaves preferentially after Arg residues. Can also cleave after citrulline (deimidated arginine) and methylarginine residues. | |||||
| Uniprot ID | ||||||
| Ensemble ID | ||||||
| HGNC ID | ||||||
Probe(s) Labeling This Target
ABPP Probe
| Probe name | Structure | Binding Site(Ratio) | Interaction ID | Ref | |
|---|---|---|---|---|---|
|
DBIA Probe Info |
 |
C59(2.80) | LDD3333 | [1] | |
Competitor(s) Related to This Target