Details of the Target
General Information of Target
| Target ID | LDTP07411 | |||||
|---|---|---|---|---|---|---|
| Target Name | Solute carrier family 35 member E4 (SLC35E4) | |||||
| Gene Name | SLC35E4 | |||||
| Gene ID | 339665 | |||||
| Synonyms |
Solute carrier family 35 member E4 |
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| 3D Structure | ||||||
| Sequence |
MCRCPPEHHDGRMTSAEVGAAAGGAQAAGPPEWPPGSPQALRQPGRARVAMAALVWLLAG
ASMSSLNKWIFTVHGFGRPLLLSALHMLVAALACHRGARRPMPGGTRCRVLLLSLTFGTS MACGNVGLRAVPLDLAQLVTTTTPLFTLALSALLLGRRHHPLQLAAMGPLCLGAACSLAG EFRTPPTGCGFLLAATCLRGLKSVQQSALLQEERLDAVTLLYATSLPSFCLLAGAALVLE AGVAPPPTAGDSRLWACILLSCLLSVLYNLASFSLLALTSALTVHVLGNLTVVGNLILSR LLFGSRLSALSYVGIALTLSGMFLYHNCEFVASWAARRGLWRRDQPSKGL |
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| Target Bioclass |
Transporter and channel
|
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| Family |
TPT transporter family, SLC35E subfamily
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| Subcellular location |
Membrane
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| Function | Putative transporter. | |||||
| Uniprot ID | ||||||
| Ensemble ID | ||||||
| HGNC ID | ||||||
Target Site Mutations in Different Cell Lines
| Cell line | Mutation details | Probe for labeling this protein in this cell | |||
|---|---|---|---|---|---|
| AN3CA | SNV: p.R158H | . | |||
| HCC44 | SNV: p.H9L Substitution: p.A20K |
. | |||
| LNCaP clone FGC | SNV: p.P38T | . | |||
| NCIH1048 | SNV: p.A52S | . | |||
| SNGM | SNV: p.R158H | . | |||
| TCCSUP | SNV: p.P132L | . | |||
| TOV21G | SNV: p.R99W | DBIA Probe Info | |||
Probe(s) Labeling This Target
ABPP Probe
| Probe name | Structure | Binding Site(Ratio) | Interaction ID | Ref | |
|---|---|---|---|---|---|
|
DBIA Probe Info |
 |
C4(1.69) | LDD3386 | [1] | |
Competitor(s) Related to This Target