Details of the Target

General Information of Target

Target ID LDTP07365
Target Name Galectin-9C (LGALS9C)
Gene Name LGALS9C
Gene ID 654346
Synonyms
Galectin-9C; Gal-9C; Galectin-9-like protein B
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MAFSGCQAPYLSPAVPFSGTIQGGLQDGFQITVNGAVLSCSGTRFAVDFQTGFSGNDIAF
HFNPRFEDGGYVVCNTRQKGTWGPEERKMHMPFQKGMPFDLCFLVQSSDFKVMVNGSLFV
QYFHRVPFHRVDTISVNGSVQLSYISFQNPRAVPVQPAFSTVPFSQPVCFPPRPRGRRQK
PPSVRPANPAPITQTVIHTVQSASGQMFSQTPAIPPMMYPHPAYPMPFITTIPGGLYPSK
SIILSGTVLPSAQRFHINLCSGSHIAFHMNPRFDENAVVRNTQINNSWGSEERSLPRKMP
FVRGQSFSVWILCEAHCLKVAVDGQHVFEYYHRLRNLPTINKLEVGGDIQLTHVQT
Target Bioclass
Other
Function Binds galactosides.
Uniprot ID
Q6DKI2
Ensemble ID
ENST00000328114.11
HGNC ID
HGNC:33874

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
IA-alkyne
 Probe Info  		C317(0.00); C74(0.00)  LDD0166  [1]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 8 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Glutamine--tRNA ligase (QARS1) Class-I aminoacyl-tRNA synthetase family P47897
NADH dehydrogenase flavoprotein 2, mitochondrial (NDUFV2) Complex I 24 kDa subunit family P19404
Nitric oxide synthase 3 (NOS3) NOS family P29474
Beta-secretase 2 (BACE2) Peptidase A1 family Q9Y5Z0
Caspase-6 (CASP6) Peptidase C14A family P55212
Kallikrein-6 (KLK6) Peptidase S1 family Q92876
Phospholipid scramblase 1 (PLSCR1) Phospholipid scramblase family O15162
Coagulation factor XIII A chain (F13A1) Transglutaminase family P00488
Transporter and channel
Click To Hide/Show 4 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Endophilin-B1 (SH3GLB1) Endophilin family Q9Y371
Junctophilin-3 (JPH3) Junctophilin family Q8WXH2
Nucleoporin p58/p45 (NUP58) NUP58 family Q9BVL2
Alpha-crystallin A chain (CRYAA) Small heat shock protein (HSP20) family P02489
Transcription factor
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Krueppel-like factor 11 (KLF11) Sp1 C2H2-type zinc-finger protein family O14901
Other
Click To Hide/Show 10 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Ataxin-1 (ATXN1) ATXN1 family P54253
Cysteine-rich tail protein 1 (CYSRT1) CYSRT1 family A8MQ03
Cytoplasmic dynein 1 heavy chain 1 (DYNC1H1) Dynein heavy chain family Q14204
Cholecystokinin (CCK) Gastrin/cholecystokinin family P06307
Axonemal dynein light intermediate polypeptide 1 (DNALI1) Inner dynein arm light chain family O14645
Glial fibrillary acidic protein (GFAP) Intermediate filament family P14136
Keratin-associated protein 6-2 (KRTAP6-2) KRTAP type 6 family Q3LI66
Disabled homolog 1 (DAB1) . O75553
RNA-binding protein with multiple splicing (RBPMS) . Q93062
TAR DNA-binding protein 43 (TARDBP) . Q13148

References

1 SP3-FAIMS Chemoproteomics for High-Coverage Profiling of the Human Cysteinome*. Chembiochem. 2021 May 14;22(10):1841-1851. doi: 10.1002/cbic.202000870. Epub 2021 Feb 18.
Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060