Details of the Target

General Information of Target

Target ID	LDTP07008
Target Name	Ras-related protein Rab-41 (RAB41)
Gene Name	RAB41
Gene ID	347517
Synonyms	Ras-related protein Rab-41
3D Structure	Download 2D Sequence (FASTA) Download 3D Structure (PDB) Download
Sequence	MSAFGHDEAWMEAGGFGLEAAERTEYQSLCKSKLLFLGEQSVGKTSIISRFMYNSFGCAC QATVGIDFLSKTMYLEDQIVQLQLWDTAGQERFHSLIPSYIRDSTIAVVVYDITNINSFK ETDKWVEHVRAERGDDVVIMLLGNKIDLDNKRQVTAEQGEEKSRNLNVMFIETSAKTGYN VKKLFRRVASALLSTRTSPPPKEGTVEIELESFEESGNRSYC
Target Bioclass	Enzyme
Family	Small GTPase superfamily, Rab family
Subcellular location	Cytoplasm
Function	Required for normal Golgi ribbon organization and ER-to-Golgi trafficking.
Uniprot ID	Q5JT25
Ensemble ID	ENST00000276066.4
HGNC ID	HGNC:18293

Probe(s) Labeling This Target

ABPP Probe

Click To Hide/Show 1 Probe Related to This Target

Probe name		Structure	Binding Site(Ratio)	Interaction ID	Ref
TFBX Probe Info			N.A.	LDD0148	[1]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Transcription factor

Click To Hide/Show 2 Protein(s) Interacting with This Target

Protein name				Family	Uniprot ID
Proto-oncogene c-Rel (REL)				.	Q04864
Transcription factor 4 (TCF4)				.	P15884

Other

Click To Hide/Show 1 Protein(s) Interacting with This Target

Protein name				Family	Uniprot ID
Pleckstrin homology domain-containing family F member 2 (PLEKHF2)				.	Q9H8W4

References

1	Chemoproteomic Profiling by Cysteine Fluoroalkylation Reveals Myrocin G as an Inhibitor of the Nonhomologous End Joining DNA Repair Pathway. J Am Chem Soc. 2021 Dec 8;143(48):20332-20342. doi: 10.1021/jacs.1c09724. Epub 2021 Nov 24. Mass spectrometry data entry: PXD029255