Details of the Target

General Information of Target

Target ID LDTP06866
Target Name Putative protein MSS51 homolog, mitochondrial (MSS51)
Gene Name MSS51
Gene ID 118490
Synonyms
ZMYND17; Putative protein MSS51 homolog, mitochondrial; Zinc finger MYND domain-containing protein 17
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MAPRSRRRRHKKPPSSVAPIIMAPTTIVTPVPLTPSKPGPSIDTLGFFSLDDNVPGLSQL
ILQKLNMKSYEEYKLVVDGGTPVSGFGFRCPQEMFQRMEDTFRFCAHCRALPSGLSDSKV
LRHCKRCRNVYYCGPECQKSDWPAHRRVCQELRLVAVDRLMEWLLVTGDFVLPSGPWPWP
PEAVQDWDSWFSMKGLHLDATLDAVLVSHAVTTLWASVGRPRPDPDVLQGSLKRLLTDVL
SRPLTLGLGLRALGIDVRRTGGSTVHVVGASHVETFLTRPGDYDELGYMFPGHLGLRVVM
VGVDVATGFSQSTSTSPLEPGTIQLSAHRGLYHDFWEEQVETGQTHHPDLVAAFHPGFHS
SPDLMEAWLPTLLLLRDYKIPTLITVYSHQELVSSLQILVELDTHITAFGSNPFMSLKPE
QVYSSPNKQPVYCSAYYIMFLGSSCQLDNRQLEEKVDGGI
Target Bioclass
Other
Uniprot ID
Q4VC12
Ensemble ID
ENST00000299432.7
HGNC ID
HGNC:21000

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
IM95 SNV: p.Y283C .
Ishikawa (Heraklio) 02 ER SNV: p.R9M .

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
Acrolein
 Probe Info  		N.A.  LDD0224  [1]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0109  NEM HeLa N.A.  LDD0224  [1]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 2 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Probable E3 ubiquitin-protein ligase DTX2 (DTX2) Deltex family Q86UW9
GTP-binding protein GEM (GEM) RGK family P55040
Transporter and channel
Click To Hide/Show 2 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Sorting nexin-18 (SNX18) Sorting nexin family Q96RF0
Sodium channel modifier 1 (SCNM1) . Q9BWG6
Immunoglobulin
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Carcinoembryonic antigen-related cell adhesion molecule 6 (CEACAM6) CEA family P40199
Other
Click To Hide/Show 14 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Protein BEX2 (BEX2) BEX family Q9BXY8
Cyclin-dependent kinase 4 inhibitor D (CDKN2D) CDKN2 cyclin-dependent kinase inhibitor family P55273
Beta-catenin-interacting protein 1 (CTNNBIP1) CTNNBIP1 family Q9NSA3
Protein FAM90A1 (FAM90A1) FAM90 family Q86YD7
Homer protein homolog 3 (HOMER3) Homer family Q9NSC5
Toll-interacting protein (TOLLIP) Tollip family Q9H0E2
WD40 repeat-containing protein SMU1 (SMU1) WD repeat SMU1 family Q2TAY7
DnaJ homolog subfamily B member 13 (DNAJB13) . P59910
KN motif and ankyrin repeat domain-containing protein 2 (KANK2) . Q63ZY3
PRKCA-binding protein (PICK1) . Q9NRD5
Proline-rich protein 35 (PRR35) . P0CG20
Protein TFG (TFG) . Q92734
Rhombotin-1 (LMO1) . P25800
Testis-specific protein 10-interacting protein (TSGA10IP) . Q3SY00

References

1 ACR-Based Probe for the Quantitative Profiling of Histidine Reactivity in the Human Proteome. J Am Chem Soc. 2023 Mar 8;145(9):5252-5260. doi: 10.1021/jacs.2c12653. Epub 2023 Feb 27.