General Information of Target

Target ID LDTP06737
Target Name Carcinoembryonic antigen-related cell adhesion molecule 16 (CEACAM16)
Gene Name CEACAM16
Gene ID 388551
Synonyms
CEAL2; Carcinoembryonic antigen-related cell adhesion molecule 16; Carcinoembryonic antigen-like 2
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MALTGYSWLLLSATFLNVGAEISITLEPAQPSEGDNVTLVVHGLSGELLAYSWYAGPTLS
VSYLVASYIVSTGDETPGPAHTGREAVRPDGSLDIQGILPRHSGTYILQTFNRQLQTEVG
YGHVQVHEILAQPTVLANSTALVERRDTLRLMCSSPSPTAEVRWFFNGGALPVALRLGLS
PDGRVLARHGIRREEAGAYQCEVWNPVSVSRSEPINLTVYFGPERVAILQDSTTRTGCTI
KVDFNTSLTLWCVSRSCPEPEYVWTFNGQALKNGQDHLNISSMTAAQEGTYTCIAKNTKT
LLSGSASVVVKLSAAAVATMIVPVPTKPTEGQDVTLTVQGYPKDLLVYAWYRGPASEPNR
LLSQLPSGTWIAGPAHTGREVGFPNCSLLVQKLNLTDTGRYTLKTVTVQGKTETLEVELQ
VAPLG
Target Bioclass
Immunoglobulin
Family
Immunoglobulin superfamily, CEA family
Subcellular location
Secreted
Function Required for proper hearing, plays a role in maintaining the integrity of the tectorial membrane.
Uniprot ID
Q2WEN9
Ensemble ID
ENST00000405314.2
HGNC ID
HGNC:31948

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
IPM
 Probe Info 
C238(7.96)  LDD1701  [1]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0023  KB03 MDA-MB-231 C238(7.96)  LDD1701  [1]

References

1 Nucleophilic covalent ligand discovery for the cysteine redoxome. Nat Chem Biol. 2023 Nov;19(11):1309-1319. doi: 10.1038/s41589-023-01330-5. Epub 2023 May 29.
Mass spectrometry data entry: PXD039908 , PXD029761