Details of the Target
General Information of Target
| Target ID | LDTP06481 | |||||
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| Target Name | Neuronal pentraxin-1 (NPTX1) |
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| Gene Name | NPTX1 | |||||
| Gene ID | 4884 | |||||
| Synonyms |
Neuronal pentraxin-1; NP1; Neuronal pentraxin I; NP-I |
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| 3D Structure | ||||||
| Sequence |
MPAGRAARTCALLALCLLGAGAQDFGPTRFICTSVPVDADMCAASVAAGGAEELRSSVLQ
LRETVLQQKETILSQKETIRELTAKLGRCESQSTLDPGAGEARAGGGRKQPGSGKNTMGD LSRTPAAETLSQLGQTLQSLKTRLENLEQYSRLNSSSQTNSLKDLLQSKIDELERQVLSR VNTLEEGKGGPRNDTEERVKIETALTSLHQRISELEKGQKDNRPGDKFQLTFPLRTNYMY AKVKKSLPEMYAFTVCMWLKSSATPGVGTPFSYAVPGQANELVLIEWGNNPMEILINDKV AKLPFVINDGKWHHICVTWTTRDGVWEAYQDGTQGGSGENLAPYHPIKPQGVLVLGQEQD TLGGGFDATQAFVGELAHFNIWDRKLTPGEVYNLATCSTKALSGNVIAWAESHIEIYGGA TKWTFEACRQIN |
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| Target Bioclass |
Transporter and channel
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| Subcellular location |
Cytoplasmic vesicle, secretory vesicle
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| Function | May be involved in mediating uptake of synaptic material during synapse remodeling or in mediating the synaptic clustering of AMPA glutamate receptors at a subset of excitatory synapses. | |||||
| Uniprot ID | ||||||
| Ensemble ID | ||||||
| HGNC ID | ||||||
Probe(s) Labeling This Target
ABPP Probe
| Probe name | Structure | Binding Site(Ratio) | Interaction ID | Ref | |
|---|---|---|---|---|---|
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IA-alkyne Probe Info |
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N.A. | LDD0165 | [1] | |
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TFBX Probe Info |
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N.A. | LDD0148 | [2] | |
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Acrolein Probe Info |
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N.A. | LDD0217 | [3] | |
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Crotonaldehyde Probe Info |
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N.A. | LDD0219 | [3] | |
Competitor(s) Related to This Target
References