Details of the Target
General Information of Target
| Target ID | LDTP06324 | |||||
|---|---|---|---|---|---|---|
| Target Name | Phosphoglucomutase-like protein 5 (PGM5) | |||||
| Gene Name | PGM5 | |||||
| Gene ID | 5239 | |||||
| Synonyms |
PGMRP; Phosphoglucomutase-like protein 5; Aciculin; Phosphoglucomutase-related protein; PGM-RP |
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| 3D Structure | ||||||
| Sequence |
MEGSPIPVLTVPTAPYEDQRPAGGGGLRRPTGLFEGQRNYLPNFIQSVLSSIDLRDRQGC
TMVVGSDGRYFSRTAIEIVVQMAAANGIGRLIIGQNGILSTPAVSCIIRKIKAAGGIILT ASHCPGGPGGEFGVKFNVANGGPAPDVVSDKIYQISKTIEEYAICPDLRIDLSRLGRQEF DLENKFKPFRVEIVDPVDIYLNLLRTIFDFHAIKGLLTGPSQLKIRIDAMHGVMGPYVRK VLCDELGAPANSAINCVPLEDFGGQHPDPNLTYATTLLEAMKGGEYGFGAAFDADGDRYM ILGQNGFFVSPSDSLAIIAANLSCIPYFRQMGVRGFGRSMPTSMALDRVAKSMKVPVYET PAGWRFFSNLMDSGRCNLCGEESFGTGSDHLREKDGLWAVLVWLSIIAARKQSVEEIVRD HWAKFGRHYYCRFDYEGLDPKTTYYIMRDLEALVTDKSFIGQQFAVGSHVYSVAKTDSFE YVDPVDGTVTKKQGLRIIFSDASRLIFRLSSSSGVRATLRLYAESYERDPSGHDQEPQAV LSPLIAIALKISQIHERTGRRGPTVIT |
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| Target Bioclass |
Enzyme
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| Family |
Phosphohexose mutase family
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| Subcellular location |
Cell junction, adherens junction
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| Function | Component of adherens-type cell-cell and cell-matrix junctions. Has no phosphoglucomutase activity in vitro. | |||||
| Uniprot ID | ||||||
| Ensemble ID | ||||||
| HGNC ID | ||||||
Target Site Mutations in Different Cell Lines
Probe(s) Labeling This Target
ABPP Probe
| Probe name | Structure | Binding Site(Ratio) | Interaction ID | Ref | |
|---|---|---|---|---|---|
|
DBIA Probe Info |
 |
C124(1.89) | LDD3337 | [1] | |
Competitor(s) Related to This Target