Details of the Target
General Information of Target
| Target ID | LDTP06132 | |||||
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| Target Name | Fibroblast growth factor-binding protein 1 (FGFBP1) |
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| Gene Name | FGFBP1 | |||||
| Gene ID | 9982 | |||||
| Synonyms |
FGFBP; HBP17; Fibroblast growth factor-binding protein 1; FGF-BP; FGF-BP1; FGF-binding protein 1; FGFBP-1; 17 kDa heparin-binding growth factor-binding protein; 17 kDa HBGF-binding protein; HBp17 |
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| 3D Structure | ||||||
| Sequence |
MKICSLTLLSFLLLAAQVLLVEGKKKVKNGLHSKVVSEQKDTLGNTQIKQKSRPGNKGKF
VTKDQANCRWAATEQEEGISLKVECTQLDHEFSCVFAGNPTSCLKLKDERVYWKQVARNL RSQKDICRYSKTAVKTRVCRKDFPESSLKLVSSTLFGNTKPRKEKTEMSPREHIKGKETT PSSLAVTQTMATKAPECVEDPDMANQRKTALEFCGETWSSLCTFFLSIVQDTSC |
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| Target Type |
Literature-reported
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| Target Bioclass |
Other
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| Family |
Fibroblast growth factor-binding protein family
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| Subcellular location |
Secreted, extracellular space
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| Function |
Acts as a carrier protein that release fibroblast-binding factors (FGFs) from the extracellular matrix (EM) storage and thus enhance the mitogenic activity of FGFs. Enhances FGF2 signaling during tissue repair, angiogenesis and in tumor growth.
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Probe(s) Labeling This Target
ABPP Probe
| Probe name | Structure | Binding Site(Ratio) | Interaction ID | Ref | |
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DBIA Probe Info |
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C197(1.45) | LDD2284 | [1] | |
Competitor(s) Related to This Target