Details of the Target
General Information of Target
| Target ID | LDTP05700 | |||||
|---|---|---|---|---|---|---|
| Target Name | Forkhead box protein F1 (FOXF1) | |||||
| Gene Name | FOXF1 | |||||
| Gene ID | 2294 | |||||
| Synonyms |
FKHL5; FREAC1; Forkhead box protein F1; Forkhead-related activator 1; FREAC-1; Forkhead-related protein FKHL5; Forkhead-related transcription factor 1 |
|||||
| 3D Structure | ||||||
| Sequence |
MSSAPEKQQPPHGGGGGGGGGGGAAMDPASSGPSKAKKTNAGIRRPEKPPYSYIALIVMA
IQSSPTKRLTLSEIYQFLQSRFPFFRGSYQGWKNSVRHNLSLNECFIKLPKGLGRPGKGH YWTIDPASEFMFEEGSFRRRPRGFRRKCQALKPMYSMMNGLGFNHLPDTYGFQGSAGGLS CPPNSLALEGGLGMMNGHLPGNVDGMALPSHSVPHLPSNGGHSYMGGCGGAAAGEYPHHD SSVPASPLLPTGAGGVMEPHAVYSGSAAAWPPSASAALNSGASYIKQQPLSPCNPAANPL SGSLSTHSLEQPYLHQNSHNAPAELQGIPRYHSQSPSMCDRKEFVFSFNAMASSSMHSAG GGSYYHQQVTYQDIKPCVM |
|||||
| Target Bioclass |
Transcription factor
|
|||||
| Subcellular location |
Nucleus
|
|||||
| Function | Probable transcription activator for a number of lung-specific genes. | |||||
| Uniprot ID | ||||||
| Ensemble ID | ||||||
| HGNC ID | ||||||
Probe(s) Labeling This Target
ABPP Probe
| Probe name | Structure | Binding Site(Ratio) | Interaction ID | Ref | |
|---|---|---|---|---|---|
|
DBIA Probe Info |
 |
C339(2.32) | LDD2440 | [1] | |
|
IA-alkyne Probe Info |
 |
N.A. | LDD0165 | [2] | |
|
IPM Probe Info |
 |
N.A. | LDD2156 | [3] | |
|
TFBX Probe Info |
 |
N.A. | LDD0148 | [4] | |
|
Acrolein Probe Info |
 |
N.A. | LDD0217 | [5] | |
|
Methacrolein Probe Info |
 |
N.A. | LDD0218 | [5] | |
Competitor(s) Related to This Target
References