Details of the Target

General Information of Target

Target ID	LDTP05350
Target Name	Semenogelin-2 (SEMG2)
Gene Name	SEMG2
Gene ID	6407
Synonyms	Semenogelin-2; Semenogelin II; SGII
3D Structure	Download 2D Sequence (FASTA) Download 3D Structure (PDB) Download
Sequence	MKSIILFVLSLLLILEKQAAVMGQKGGSKGQLPSGSSQFPHGQKGQHYFGQKDQQHTKSK GSFSIQHTYHVDINDHDWTRKSQQYDLNALHKATKSKQHLGGSQQLLNYKQEGRDHDKSK GHFHMIVIHHKGGQAHHGTQNPSQDQGNSPSGKGLSSQCSNTEKRLWVHGLSKEQASASG AQKGRTQGGSQSSYVLQTEELVVNKQQRETKNSHQNKGHYQNVVDVREEHSSKLQTSLHP AHQDRLQHGPKDIFTTQDELLVYNKNQHQTKNLSQDQEHGRKAHKISYPSSRTEERQLHH GEKSVQKDVSKGSISIQTEEKIHGKSQNQVTIHSQDQEHGHKENKISYQSSSTEERHLNC GEKGIQKGVSKGSISIQTEEQIHGKSQNQVRIPSQAQEYGHKENKISYQSSSTEERRLNS GEKDVQKGVSKGSISIQTEEKIHGKSQNQVTIPSQDQEHGHKENKMSYQSSSTEERRLNY GGKSTQKDVSQSSISFQIEKLVEGKSQIQTPNPNQDQWSGQNAKGKSGQSADSKQDLLSH EQKGRYKQESSESHNIVITEHEVAQDDHLTQQYNEDRNPIST
Target Bioclass	Other
Family	Semenogelin family
Subcellular location	Secreted
Function	Participates in the formation of a gel matrix (sperm coagulum) entrapping the accessory gland secretions and ejaculated spermatozoa.
Uniprot ID	Q02383
Ensemble ID	ENST00000372769.4
HGNC ID	HGNC:10743

Probe(s) Labeling This Target

ABPP Probe

Click To Hide/Show 1 Probe Related to This Target

Probe name		Structure	Binding Site(Ratio)	Interaction ID	Ref
ATP probe Probe Info			N.A.	LDD0199	[1]

The Interaction Atlas With This Target

The Drug(s) Related To This Target

Approved

Click To Hide/Show 2 Drug(s) Interacting with This Target

Drug Name				Drug Type	External ID
Zinc Chloride				.	DB14533
Zinc Sulfate Unspecified Form				.	DB14548

References

1	Targeted Proteomic Approaches for Proteome-Wide Characterizations of the AMP-Binding Capacities of Kinases. J Proteome Res. 2022 Aug 5;21(8):2063-2070. doi: 10.1021/acs.jproteome.2c00225. Epub 2022 Jul 12.