Details of the Target

General Information of Target

Target ID LDTP05263
Target Name Pregnancy-specific beta-1-glycoprotein 6 (PSG6)
Gene Name PSG6
Gene ID 5675
Synonyms
CGM3; PSG10; PSG12; PSGGB; Pregnancy-specific beta-1-glycoprotein 6; PS-beta-G-6; PSBG-6; Pregnancy-specific glycoprotein 6; Pregnancy-specific beta-1-glycoprotein 10; PS-beta-G-10; PSBG-10; Pregnancy-specific glycoprotein 10; Pregnancy-specific beta-1-glycoprotein 12; PS-beta-G-12; PSBG-12; Pregnancy-specific glycoprotein 12
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MGPLSAPPCTQHITWKGLLLTASLLNFWNLPTTAQVIIEAKPPKVSEGKDVLLLVHNLPQ
NLTGYIWYKGQMTDLYHYITSYVVHGQIIYGPAYSGRETVYSNASLLIQNVTQEDAGSYT
LHIIKRGDGTGGVTGYFTVTLYSETPKPSISSSNLNPREVMEAVRLICDPETPDASYLWL
LNGQNLPMTHRLQLSKTNRTLYLFGVTKYIAGPYECEIRNPVSASRSDPVTLNLLPKLPM
PYITINNLNPREKKDVLAFTCEPKSRNYTYIWWLNGQSLPVSPRVKRPIENRILILPSVT
RNETGPYQCEIRDRYGGIRSNPVTLNVLYGPDLPRIYPSFTYYRSGENLDLSCFADSNPP
AEYSWTINGKFQLSGQKLFIPQITTNHSGLYACSVRNSATGKEISKSMIVKVSETASPQV
TYAGPNTWFQEILLL
Target Bioclass
Immunoglobulin
Family
Immunoglobulin superfamily, CEA family
Subcellular location
Secreted
Uniprot ID
Q00889
Ensemble ID
ENST00000187910.7
HGNC ID
HGNC:9523

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info  		C217(3.60)  LDD2284  [1]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0022  KB02 CAL-120 C217(3.60)  LDD2284  [1]
 LDCM0023  KB03 CAL-120 C217(5.41)  LDD2701  [1]
 LDCM0024  KB05 CAL-120 C217(4.95)  LDD3118  [1]

References

1 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840