Details of the Target
General Information of Target
| Target ID | LDTP05121 | |||||
|---|---|---|---|---|---|---|
| Target Name | Cyclin-A1 (CCNA1) | |||||
| Gene Name | CCNA1 | |||||
| Gene ID | 8900 | |||||
| Synonyms |
Cyclin-A1 |
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| 3D Structure | ||||||
| Sequence |
METGFPAIMYPGSFIGGWGEEYLSWEGPGLPDFVFQQQPVESEAMHCSNPKSGVVLATVA
RGPDACQILTRAPLGQDPPQRTVLGLLTANGQYRRTCGQGITRIRCYSGSENAFPPAGKK ALPDCGVQEPPKQGFDIYMDELEQGDRDSCSVREGMAFEDVYEVDTGTLKSDLHFLLDFN TVSPMLVDSSLLSQSEDISSLGTDVINVTEYAEEIYQYLREAEIRHRPKAHYMKKQPDIT EGMRTILVDWLVEVGEEYKLRAETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASKY EEIYPPEVDEFVYITDDTYTKRQLLKMEHLLLKVLAFDLTVPTTNQFLLQYLRRQGVCVR TENLAKYVAELSLLEADPFLKYLPSLIAAAAFCLANYTVNKHFWPETLAAFTGYSLSEIV PCLSELHKAYLDIPHRPQQAIREKYKASKYLCVSLMEPPAVLLLQ |
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| Target Bioclass |
Other
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| Family |
Cyclin family, Cyclin AB subfamily
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| Subcellular location |
Nucleus
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| Function |
May be involved in the control of the cell cycle at the G1/S (start) and G2/M (mitosis) transitions. May primarily function in the control of the germline meiotic cell cycle and additionally in the control of mitotic cell cycle in some somatic cells.
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| Uniprot ID | ||||||
| Ensemble ID | ||||||
| HGNC ID | ||||||
| ChEMBL ID | ||||||
Target Site Mutations in Different Cell Lines
Probe(s) Labeling This Target
ABPP Probe
| Probe name | Structure | Binding Site(Ratio) | Interaction ID | Ref | |
|---|---|---|---|---|---|
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DBIA Probe Info |
 |
C97(1.50) | LDD3333 | [1] | |
Competitor(s) Related to This Target