Details of the Target

General Information of Target

Target ID LDTP04984
Target Name Protein BTG1 (BTG1)
Gene Name BTG1
Gene ID 694
Synonyms
Protein BTG1; B-cell translocation gene 1 protein
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MHPFYTRAATMIGEIAAAVSFISKFLRTKGLTSERQLQTFSQSLQELLAEHYKHHWFPEK
PCKGSGYRCIRINHKMDPLIGQAAQRIGLSSQELFRLLPSELTLWVDPYEVSYRIGEDGS
ICVLYEASPAGGSTQNSTNVQMVDSRISCKEELLLGRTSPSKNYNMMTVSG
Target Type
Literature-reported
Target Bioclass
Other
Family
BTG family
Function Anti-proliferative protein.
TTD ID
T45357
Uniprot ID
P62324
DrugMap ID
TTL7N2W
Ensemble ID
ENST00000256015.5
HGNC ID
HGNC:1130

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
IA-alkyne
 Probe Info  		C149(0.46)  LDD2183  [1]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0625  F8 Ramos C149(0.42)  LDD2187  [1]
 LDCM0576  Fragment14 Ramos C149(0.68)  LDD2193  [1]
 LDCM0586  Fragment28 Ramos C149(0.58)  LDD2198  [1]
 LDCM0566  Fragment4 Ramos C149(0.59)  LDD2184  [1]
 LDCM0023  KB03 Ramos C149(0.46)  LDD2183  [1]

References

1 Site-specific quantitative cysteine profiling with data-independent acquisition-based mass spectrometry. Methods Enzymol. 2023;679:295-322. doi: 10.1016/bs.mie.2022.07.037. Epub 2022 Sep 7.
Mass spectrometry data entry: PXD027578