Details of the Target
General Information of Target
| Target ID | LDTP04732 | |||||
|---|---|---|---|---|---|---|
| Target Name | Cathepsin W (CTSW) | |||||
| Gene Name | CTSW | |||||
| Gene ID | 1521 | |||||
| Synonyms |
Cathepsin W; EC 3.4.22.-; Lymphopain |
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| 3D Structure | ||||||
| Sequence |
MALTAHPSCLLALLVAGLAQGIRGPLRAQDLGPQPLELKEAFKLFQIQFNRSYLSPEEHA
HRLDIFAHNLAQAQRLQEEDLGTAEFGVTPFSDLTEEEFGQLYGYRRAAGGVPSMGREIR SEEPEESVPFSCDWRKVASAISPIKDQKNCNCCWAMAAAGNIETLWRISFWDFVDVSVQE LLDCGRCGDGCHGGFVWDAFITVLNNSGLASEKDYPFQGKVRAHRCHPKKYQKVAWIQDF IMLQNNEHRIAQYLATYGPITVTINMKPLQLYRKGVIKATPTTCDPQLVDHSVLLVGFGS VKSEEGIWAETVSSQSQPQPPHPTPYWILKNSWGAQWGEKGYFRLHRGSNTCGITKFPLT ARVQKPDMKPRVSCPP |
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| Target Bioclass |
Enzyme
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| Family |
Peptidase C1 family
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| Subcellular location |
Endoplasmic reticulum
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| Function |
May have a specific function in the mechanism or regulation of T-cell cytolytic activity.; (Microbial infection) Plays a role during influenza virus infection in lungs cells ex vivo. Acts at the level of virus entering host cytoplasm from late endosome.
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| Uniprot ID | ||||||
| Ensemble ID | ||||||
| HGNC ID | ||||||
Probe(s) Labeling This Target
ABPP Probe
| Probe name | Structure | Binding Site(Ratio) | Interaction ID | Ref | |
|---|---|---|---|---|---|
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IA-alkyne Probe Info |
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C352(5.69) | LDD1705 | [1] | |
Competitor(s) Related to This Target