Details of the Target
General Information of Target
| Target ID | LDTP04648 | |||||
|---|---|---|---|---|---|---|
| Target Name | ADP-ribosylhydrolase ARH1 (ADPRH) | |||||
| Gene Name | ADPRH | |||||
| Gene ID | 141 | |||||
| Synonyms |
ARH1; ADP-ribosylhydrolase ARH1; EC 3.2.2.19; ADP-ribose-L-arginine cleaving enzyme; [Protein ADP-ribosylarginine] hydrolase; ADP-ribosylarginine hydrolase; hARH1 |
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| 3D Structure | ||||||
| Sequence |
MEKYVAAMVLSAAGDALGYYNGKWEFLQDGEKIHRQLAQLGGLDALDVGRWRVSDDTVMH
LATAEALVEAGKAPKLTQLYYLLAKHYQDCMEDMDGRAPGGASVHNAMQLKPGKPNGWRI PFNSHEGGCGAAMRAMCIGLRFPHHSQLDTLIQVSIESGRMTHHHPTGYLGALASALFTA YAVNSRPPLQWGKGLMELLPEAKKYIVQSGYFVEENLQHWSYFQTKWENYLKLRGILDGE SAPTFPESFGVKERDQFYTSLSYSGWGGSSGHDAPMIAYDAVLAAGDSWKELAHRAFFHG GDSDSTAAIAGCWWGVMYGFKGVSPSNYEKLEYRNRLEETARALYSLGSKEDTVISL |
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| Target Bioclass |
Enzyme
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| Family |
ADP-ribosylglycohydrolase family
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| Function | Specifically acts as an arginine mono-ADP-ribosylhydrolase by mediating the removal of mono-ADP-ribose attached to arginine residues on proteins. | |||||
| Uniprot ID | ||||||
| Ensemble ID | ||||||
| HGNC ID | ||||||
Probe(s) Labeling This Target
ABPP Probe
| Probe name | Structure | Binding Site(Ratio) | Interaction ID | Ref | |
|---|---|---|---|---|---|
|
DBIA Probe Info |
 |
C129(1.52) | LDD3333 | [1] | |
Competitor(s) Related to This Target