Details of the Target

General Information of Target

Target ID LDTP04599
Target Name Cysteine-rich secretory protein 3 (CRISP3)
Gene Name CRISP3
Gene ID 10321
Synonyms
Cysteine-rich secretory protein 3; CRISP-3; Specific granule protein of 28 kDa; SGP28
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MTLFPVLLFLVAGLLPSFPANEDKDPAFTALLTTQTQVQREIVNKHNELRRAVSPPARNM
LKMEWNKEAAANAQKWANQCNYRHSNPKDRMTSLKCGENLYMSSASSSWSQAIQSWFDEY
NDFDFGVGPKTPNAVVGHYTQVVWYSSYLVGCGNAYCPNQKVLKYYYVCQYCPAGNWANR
LYVPYEQGAPCASCPDNCDDGLCTNGCKYEDLYSNCKSLKLTLTCKHQLVRDSCKASCNC
SNSIY
Target Bioclass
Other
Family
CRISP family
Subcellular location
Secreted
Uniprot ID
P54108
Ensemble ID
ENST00000263045.9
HGNC ID
HGNC:16904

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info  		C239(5.92)  LDD3486  [1]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0022  KB02 BRX330 C239(1.94)  LDD2271  [1]
 LDCM0023  KB03 BRX330 C239(1.44)  LDD2688  [1]
 LDCM0024  KB05 VCaP C239(5.92)  LDD3486  [1]

References

1 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840