Details of the Target
General Information of Target
| Target ID | LDTP04220 | |||||
|---|---|---|---|---|---|---|
| Target Name | Troponin I, fast skeletal muscle (TNNI2) | |||||
| Gene Name | TNNI2 | |||||
| Gene ID | 7136 | |||||
| Synonyms |
Troponin I, fast skeletal muscle; Troponin I, fast-twitch isoform |
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| 3D Structure | ||||||
| Sequence |
MGDEEKRNRAITARRQHLKSVMLQIAATELEKEESRREAEKQNYLAEHCPPLHIPGSMSE
VQELCKQLHAKIDAAEEEKYDMEVRVQKTSKELEDMNQKLFDLRGKFKRPPLRRVRMSAD AMLKALLGSKHKVCMDLRANLKQVKKEDTEKERDLRDVGDWRKNIEEKSGMEGRKKMFES ES |
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| Target Bioclass |
Other
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| Family |
Troponin I family
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| Function | Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. | |||||
| Uniprot ID | ||||||
| Ensemble ID | ||||||
| HGNC ID | ||||||
| ChEMBL ID | ||||||
Probe(s) Labeling This Target
ABPP Probe
| Probe name | Structure | Binding Site(Ratio) | Interaction ID | Ref | |
|---|---|---|---|---|---|
|
STPyne Probe Info |
 |
K130(0.31) | LDD0277 | [1] | |