Details of the Target
General Information of Target
| Target ID | LDTP04182 | |||||
|---|---|---|---|---|---|---|
| Target Name | Aldehyde dehydrogenase family 3 member B2 (ALDH3B2) | |||||
| Gene Name | ALDH3B2 | |||||
| Synonyms |
ALDH8; Aldehyde dehydrogenase family 3 member B2; EC 1.2.1.3; Aldehyde dehydrogenase 8 |
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| 3D Structure | ||||||
| Sequence |
MKDEPRSTNLFMKLDSVFIWKEPFGLVLIIAPWNYPLNLTLVLLVGALAAGSCVVLKPSE
ISQGTEKVLAEVLPQYLDQSCFAVVLGGPQETGQLLEHKLDYIFFTGSPRVGKIVMTAAT KHLTPVTLELGGKNPCYVDDNCDPQTVANRVAWFCYFNAGQTCVAPDYVLCSPEMQERLL PALQSTITRFYGDDPQSSPNLGHIINQKQFQRLRALLGCSRVAIGGQSNESDRYIAPTVL VDVQETEPVMQEEIFGPILPIVNVQSVDEAIKFINRQEKPLALYAFSNSSQVVNQMLERT SSGSFGGNEGFTYISLLSVPFGGVGHSGMGRYHGKFTFDTFSHHRTCLLAPSGLEKLKEI HYPPYTDWNQQLLRWGMGSQSCTLL |
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| Target Bioclass |
Enzyme
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| Family |
Aldehyde dehydrogenase family
|
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| Subcellular location |
Lipid droplet
|
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| Function | Oxidizes medium and long chain aldehydes into non-toxic fatty acids. | |||||
| Uniprot ID | ||||||
| Ensemble ID | ||||||
| HGNC ID | ||||||
| ChEMBL ID | ||||||
Probe(s) Labeling This Target
ABPP Probe
| Probe name | Structure | Binding Site(Ratio) | Interaction ID | Ref | |
|---|---|---|---|---|---|
|
AZ-9 Probe Info |
 |
E129(0.90) | LDD2208 | [1] | |