Details of the Target
General Information of Target
| Target ID | LDTP04044 | |||||
|---|---|---|---|---|---|---|
| Target Name | Melanoma-associated antigen 11 (MAGEA11) | |||||
| Gene Name | MAGEA11 | |||||
| Gene ID | 4110 | |||||
| Synonyms |
MAGE11; Melanoma-associated antigen 11; Cancer/testis antigen 1.11; CT1.11; MAGE-11 antigen |
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| 3D Structure | ||||||
| Sequence |
METQFRRGGLGCSPASIKRKKKREDSGDFGLQVSTMFSEDDFQSTERAPYGPQLQWSQDL
PRVQVFREQANLEDRSPRRTQRITGGEQVLWGPITQIFPTVRPADLTRVIMPLEQRSQHC KPEEGLQAQEEDLGLVGAQALQAEEQEAAFFSSTLNVGTLEELPAAESPSPPQSPQEESF SPTAMDAIFGSLSDEGSGSQEKEGPSTSPDLIDPESFSQDILHDKIIDLVHLLLRKYRVK GLITKAEMLGSVIKNYEDYFPEIFREASVCMQLLFGIDVKEVDPTSHSYVLVTSLNLSYD GIQCNEQSMPKSGLLIIVLGVIFMEGNCIPEEVMWEVLSIMGVYAGREHFLFGEPKRLLT QNWVQEKYLVYRQVPGTDPACYEFLWGPRAHAETSKMKVLEYIANANGRDPTSYPSLYED ALREEGEGV |
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| Target Bioclass |
Other
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| Subcellular location |
Nucleus
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| Function |
Acts as androgen receptor coregulator that increases androgen receptor activity by modulating the receptors interdomain interaction. May play a role in embryonal development and tumor transformation or aspects of tumor progression.
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| Uniprot ID | ||||||
| Ensemble ID | ||||||
| HGNC ID | ||||||
Target Site Mutations in Different Cell Lines
Probe(s) Labeling This Target
ABPP Probe
| Probe name | Structure | Binding Site(Ratio) | Interaction ID | Ref | |
|---|---|---|---|---|---|
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DBIA Probe Info |
 |
C381(1.04) | LDD3364 | [1] | |
Competitor(s) Related to This Target