General Information of Target

Target ID LDTP03581
Target Name Homeobox protein Hox-A7 (HOXA7)
Gene Name HOXA7
Gene ID 3204
Synonyms
HOX1A; Homeobox protein Hox-A7; Homeobox protein Hox 1.1; Homeobox protein Hox-1A
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MSSSYYVNALFSKYTAGASLFQNAEPTSCSFAPNSQRSGYGAGAGAFASTVPGLYNVNSP
LYQSPFASGYGLGADAYGNLPCASYDQNIPGLCSDLAKGACDKTDEGALHGAAEANFRIY
PWMRSSGPDRKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQN
RRMKWKKEHKDEGPTAAAAPEGAVPSAAATAAADKADEEDDDEEEEDEEE
Target Type
Literature-reported
Target Bioclass
Transcription factor
Family
Antp homeobox family
Subcellular location
Nucleus
Function Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
TTD ID
T26338
Uniprot ID
P31268
DrugMap ID
TTMRE4Q
Ensemble ID
ENST00000242159.5
HGNC ID
HGNC:5108

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 2 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
JW-RF-010
 Probe Info 
N.A.  LDD0026  [1]
TFBX
 Probe Info 
N.A.  LDD0027  [1]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Transporter and channel
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Syntenin-1 (SDCBP) . O00560

References

1 Chemoproteomic Profiling by Cysteine Fluoroalkylation Reveals Myrocin G as an Inhibitor of the Nonhomologous End Joining DNA Repair Pathway. J Am Chem Soc. 2021 Dec 8;143(48):20332-20342. doi: 10.1021/jacs.1c09724. Epub 2021 Nov 24.
Mass spectrometry data entry: PXD029255