Details of the Target
General Information of Target
| Target ID | LDTP03472 | |||||
|---|---|---|---|---|---|---|
| Target Name | Adenosine receptor A2b (ADORA2B) | |||||
| Gene Name | ADORA2B | |||||
| Gene ID | 136 | |||||
| Synonyms |
Adenosine receptor A2b |
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| 3D Structure | ||||||
| Sequence |
MLLETQDALYVALELVIAALSVAGNVLVCAAVGTANTLQTPTNYFLVSLAAADVAVGLFA
IPFAITISLGFCTDFYGCLFLACFVLVLTQSSIFSLLAVAVDRYLAICVPLRYKSLVTGT RARGVIAVLWVLAFGIGLTPFLGWNSKDSATNNCTEPWDGTTNESCCLVKCLFENVVPMS YMVYFNFFGCVLPPLLIMLVIYIKIFLVACRQLQRTELMDHSRTTLQREIHAAKSLAMIV GIFALCWLPVHAVNCVTLFQPAQGKNKPKWAMNMAILLSHANSVVNPIVYAYRNRDFRYT FHKIISRYLLCQADVKSGNGQAGVQPALGVGL |
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| Target Type |
Successful
|
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| Target Bioclass |
GPCR
|
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| Family |
G-protein coupled receptor 1 family
|
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| Subcellular location |
Cell membrane
|
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| Function | Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. | |||||
| TTD ID | ||||||
| Uniprot ID | ||||||
| DrugMap ID | ||||||
| Ensemble ID | ||||||
| HGNC ID | ||||||
| ChEMBL ID | ||||||
Probe(s) Labeling This Target
ABPP Probe
| Probe name | Structure | Binding Site(Ratio) | Interaction ID | Ref | |
|---|---|---|---|---|---|
|
DBIA Probe Info |
 |
C311(3.50) | LDD3440 | [1] | |
Competitor(s) Related to This Target