Details of the Target

General Information of Target

Target ID LDTP03269
Target Name Zinc finger and BTB domain-containing protein 25 (ZBTB25)
Gene Name ZBTB25
Gene ID 7597
Synonyms
C14orf51; KUP; ZNF46; Zinc finger and BTB domain-containing protein 25; Zinc finger protein 46; Zinc finger protein KUP
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MDTASHSLVLLQQLNMQREFGFLCDCTVAIGDVYFKAHRAVLAAFSNYFKMIFIHQTSEC
IKIQPTDIQPDIFSYLLHIMYTGKGPKQIVDHSRLEEGIRFLHADYLSHIATEMNQVFSP
ETVQSSNLYGIQISTTQKTVVKQGLEVKEAPSSNSGNRAAVQGDHPQLQLSLAIGLDDGT
ADQQRACPATQALEEHQKPPVSIKQERCDPESVISQSHPSPSSEVTGPTFTENSVKIHLC
HYCGERFDSRSNLRQHLHTHVSGSLPFGVPASILESNDLGEVHPLNENSEALECRRLSSF
IVKENEQQPDHTNRGTTEPLQISQVSLISKDTEPVELNCNFSFSRKRKMSCTICGHKFPR
KSQLLEHMYTHKGKSYRYNRCQRFGNALAQRFQPYCDSWSDVSLKSSRLSQEHLDLPCAL
ESELTQENVDTILVE
Target Bioclass
Transcription factor
Subcellular location
Nucleus
Function May be involved in transcriptional regulation.
Uniprot ID
P24278
Ensemble ID
ENST00000394715.1
HGNC ID
HGNC:13112

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info  		C187(0.97)  LDD1571  [1]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0367  CL1 HEK-293T C187(0.97)  LDD1571  [1]
 LDCM0370  CL101 HEK-293T C187(0.88)  LDD1574  [1]
 LDCM0374  CL105 HEK-293T C187(1.04)  LDD1578  [1]
 LDCM0378  CL109 HEK-293T C187(1.03)  LDD1582  [1]
 LDCM0383  CL113 HEK-293T C187(1.07)  LDD1587  [1]
 LDCM0387  CL117 HEK-293T C187(1.00)  LDD1591  [1]
 LDCM0392  CL121 HEK-293T C187(0.95)  LDD1596  [1]
 LDCM0396  CL125 HEK-293T C187(1.08)  LDD1600  [1]
 LDCM0400  CL13 HEK-293T C187(1.02)  LDD1604  [1]
 LDCM0413  CL25 HEK-293T C187(0.85)  LDD1617  [1]
 LDCM0426  CL37 HEK-293T C187(1.05)  LDD1630  [1]
 LDCM0439  CL49 HEK-293T C187(0.98)  LDD1643  [1]
 LDCM0453  CL61 HEK-293T C187(0.89)  LDD1656  [1]
 LDCM0466  CL73 HEK-293T C187(0.98)  LDD1669  [1]
 LDCM0479  CL85 HEK-293T C187(0.92)  LDD1682  [1]
 LDCM0492  CL97 HEK-293T C187(0.93)  LDD1695  [1]

References

1 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402