Details of the Target
General Information of Target
| Target ID | LDTP03267 | |||||
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| Target Name | Immunoglobulin alpha Fc receptor (FCAR) |
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| Gene Name | FCAR | |||||
| Gene ID | 2204 | |||||
| Synonyms |
CD89; Immunoglobulin alpha Fc receptor; IgA Fc receptor; CD antigen CD89 |
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| 3D Structure | ||||||
| Sequence |
MDPKQTTLLCLVLCLGQRIQAQEGDFPMPFISAKSSPVIPLDGSVKIQCQAIREAYLTQL
MIIKNSTYREIGRRLKFWNETDPEFVIDHMDANKAGRYQCQYRIGHYRFRYSDTLELVVT GLYGKPFLSADRGLVLMPGENISLTCSSAHIPFDRFSLAKEGELSLPQHQSGEHPANFSL GPVDLNVSGIYRCYGWYNRSPYLWSFPSNALELVVTDSIHQDYTTQNLIRMAVAGLVLVA LLAILVENWHSHTALNKEASADVAEPSWSQQMCQPGLTFARTPSVCK |
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| Target Type |
Discontinued
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| Target Bioclass |
Immunoglobulin
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| Subcellular location |
Secreted; Cell membrane
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| Function | Binds to the Fc region of immunoglobulins alpha. Mediates several functions including cytokine production. | |||||
| TTD ID | ||||||
| Uniprot ID | ||||||
| DrugMap ID | ||||||
| Ensemble ID | ||||||
| HGNC ID | ||||||
Target Site Mutations in Different Cell Lines
Probe(s) Labeling This Target
ABPP Probe
| Probe name | Structure | Binding Site(Ratio) | Interaction ID | Ref | |
|---|---|---|---|---|---|
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DBIA Probe Info |
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C75(2.70) | LDD3336 | [1] | |
Competitor(s) Related to This Target