General Information of Target

Target ID LDTP03241
Target Name Oligodendrocyte-myelin glycoprotein (OMG)
Gene Name OMG
Gene ID 4974
Synonyms
OMGP; Oligodendrocyte-myelin glycoprotein
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MEYQILKMSLCLFILLFLTPGILCICPLQCICTERHRHVDCSGRNLSTLPSGLQENIIHL
NLSYNHFTDLHNQLTQYTNLRTLDISNNRLESLPAHLPRSLWNMSAANNNIKLLDKSDTA
YQWNLKYLDVSKNMLEKVVLIKNTLRSLEVLNLSSNKLWTVPTNMPSKLHIVDLSNNSLT
QILPGTLINLTNLTHLYLHNNKFTFIPDQSFDQLFQLQEITLYNNRWSCDHKQNITYLLK
WMMETKAHVIGTPCSTQISSLKEHNMYPTPSGFTSSLFTVSGMQTVDTINSLSVVTQPKV
TKIPKQYRTKETTFGATLSKDTTFTSTDKAFVPYPEDTSTETINSHEAAAATLTIHLQDG
MVTNTSLTSSTKSSPTPMTLSITSGMPNNFSEMPQQSTTLNLWREETTTNVKTPLPSVAN
AWKVNASFLLLLNVVVMLAV
Target Bioclass
Other
Subcellular location
Cell membrane
Function Cell adhesion molecule contributing to the interactive process required for myelination in the central nervous system.
Uniprot ID
P23515
Ensemble ID
ENST00000247271.5
HGNC ID
HGNC:8135

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info 
C41(1.31)  LDD2253  [1]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0022  KB02 A2058 C41(1.31)  LDD2253  [1]
 LDCM0023  KB03 A2058 C41(1.51)  LDD2670  [1]
 LDCM0024  KB05 A2058 C41(1.50)  LDD3087  [1]

References

1 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840