Details of the Target
General Information of Target
| Target ID | LDTP03218 | |||||
|---|---|---|---|---|---|---|
| Target Name | Sarcoplasmic reticulum histidine-rich calcium-binding protein (HRC) | |||||
| Gene Name | HRC | |||||
| Gene ID | 3270 | |||||
| Synonyms |
HCP; Sarcoplasmic reticulum histidine-rich calcium-binding protein |
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| 3D Structure | ||||||
| Sequence |
MGHHRPWLHASVLWAGVASLLLPPAMTQQLRGDGLGFRNRNNSTGVAGLSEEASAELRHH
LHSPRDHPDENKDVSTENGHHFWSHPDREKEDEDVSKEYGHLLPGHRSQDHKVGDEGVSG EEVFAEHGGQARGHRGHGSEDTEDSAEHRHHLPSHRSHSHQDEDEDEVVSSEHHHHILRH GHRGHDGEDDEGEEEEEEEEEEEEASTEYGHQAHRHRGHGSEEDEDVSDGHHHHGPSHRH QGHEEDDDDDDDDDDDDDDDDVSIEYRHQAHRHQGHGIEEDEDVSDGHHHRDPSHRHRSH EEDDNDDDDVSTEYGHQAHRHQDHRKEEVEAVSGEHHHHVPDHRHQGHRDEEEDEDVSTE RWHQGPQHVHHGLVDEEEEEEEITVQFGHYVASHQPRGHKSDEEDFQDEYKTEVPHHHHH RVPREEDEEVSAELGHQAPSHRQSHQDEETGHGQRGSIKEMSHHPPGHTVVKDRSHLRKD DSEEEKEKEEDPGSHEEDDESSEQGEKGTHHGSRDQEDEEDEEEGHGLSLNQEEEEEEDK EEEEEEEDEERREERAEVGAPLSPDHSEEEEEEEEGLEEDEPRFTIIPNPLDRREEAGGA SSEEESGEDTGPQDAQEYGNYQPGSLCGYCSFCNRCTECESCHCDEENMGEHCDQCQHCQ FCYLCPLVCETVCAPGSYVDYFSSSLYQALADMLETPEP |
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| Target Type |
Literature-reported
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| Target Bioclass |
Other
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| Family |
HRC family
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| Subcellular location |
Sarcoplasmic reticulum lumen
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| Function | May play a role in the regulation of calcium sequestration or release in the SR of skeletal and cardiac muscle. | |||||
| TTD ID | ||||||
| Uniprot ID | ||||||
| DrugMap ID | ||||||
| Ensemble ID | ||||||
| HGNC ID | ||||||
Probe(s) Labeling This Target
ABPP Probe
| Probe name | Structure | Binding Site(Ratio) | Interaction ID | Ref | |
|---|---|---|---|---|---|
|
YN-1 Probe Info |
 |
D548(0.00); E549(0.00) | LDD0447 | [1] | |
The Interaction Atlas With This Target