General Information of Target

Target ID LDTP02615
Target Name Prolactin-inducible protein (PIP)
Gene Name PIP
Gene ID 5304
Synonyms
GCDFP15; GPIP4; Prolactin-inducible protein; Gross cystic disease fluid protein 15; GCDFP-15; Prolactin-induced protein; Secretory actin-binding protein; SABP; gp17
3D Structure
Download
2D Sequence (FASTA)
Download
3D Structure (PDB)
Download
Sequence
MRLLQLLFRASPATLLLVLCLQLGANKAQDNTRKIIIKNFDIPKSVRPNDEVTAVLAVQT
ELKECMVVKTYLISSIPLQGAFNYKYTACLCDDNPKTFYWDFYTNRTVQIAAVVDVIREL
GICPDDAAVIPIKNNRFYTIEILKVE
Target Bioclass
Other
Family
PIP family
Subcellular location
Secreted
Uniprot ID
P12273
Ensemble ID
ENST00000291009.4
HGNC ID
HGNC:8993

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info 
C123(1.88)  LDD2268  [1]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0022  KB02 BRX211 C123(1.88)  LDD2268  [1]
 LDCM0023  KB03 BRX211 C123(2.98)  LDD2685  [1]
 LDCM0024  KB05 BRX211 C123(2.66)  LDD3102  [1]

References

1 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840