General Information of Target

Target ID LDTP02574
Target Name Fibroblast growth factor 3 (FGF3)
Gene Name FGF3
Gene ID 2248
Synonyms
INT2; Fibroblast growth factor 3; FGF-3; Heparin-binding growth factor 3; HBGF-3; Proto-oncogene Int-2
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MGLIWLLLLSLLEPGWPAAGPGARLRRDAGGRGGVYEHLGGAPRRRKLYCATKYHLQLHP
SGRVNGSLENSAYSILEITAVEVGIVAIRGLFSGRYLAMNKRGRLYASEHYSAECEFVER
IHELGYNTYASRLYRTVSSTPGARRQPSAERLWYVSVNGKGRPRRGFKTRRTQKSSLFLP
RVLDHRDHEMVRQLQSGLPRPPGKGVQPRRRRQKQSPDNLEPSHVQASRLGSQLEASAH
Target Bioclass
Other
Family
Heparin-binding growth factors family
Subcellular location
Secreted
Function Plays an important role in the regulation of embryonic development, cell proliferation, and cell differentiation. Required for normal ear development.
Uniprot ID
P11487
Ensemble ID
ENST00000334134.4
HGNC ID
HGNC:3681

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
W1
 Probe Info 
N.A.  LDD0236  [1]

References

1 Oxidant-Induced Bioconjugation for Protein Labeling in Live Cells. ACS Chem Biol. 2023 Jan 20;18(1):112-122. doi: 10.1021/acschembio.2c00740. Epub 2022 Dec 21.