Details of the Target
General Information of Target
| Target ID | LDTP02450 | |||||
|---|---|---|---|---|---|---|
| Target Name | EEF1A lysine methyltransferase 4 (EEF1AKMT4) | |||||
| Gene Name | EEF1AKMT4 | |||||
| Gene ID | 110599564 | |||||
| Synonyms |
EEF1A lysine methyltransferase 4; EC 2.1.1.- |
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| 3D Structure | ||||||
| Sequence |
MASPGAGRAPPELPERNCGYREVEYWDQRYQGAADSAPYDWFGDFSSFRALLEPELRPED
RILVLGCGNSALSYELFLGGFPNVTSVDYSSVVVAAMQARHAHVPQLRWETMDVRKLDFP SASFDVVLEKGTLDALLAGERDPWTVSSEGVHTVDQVLSEVSRVLVPGGRFISMTSAAPH FRTRHYAQAYYGWSLRHATYGSGFHFHLYLMHKGGKLSVAQLALGAQILSPPRPPTSPCF LQDSDHEDFLSAIQL |
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| Target Bioclass |
Enzyme
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| Family |
Methyltransferase superfamily
|
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| Function | Protein-lysine methyltransferase that efficiently catalyzes three successive methylations on 'Lys-36' in eukaryotic translation elongation factor 1 alpha (EEF1A1 or EEF1A2). | |||||
| Uniprot ID | ||||||
| Ensemble ID | ||||||
| HGNC ID | ||||||
Probe(s) Labeling This Target
ABPP Probe
| Probe name | Structure | Binding Site(Ratio) | Interaction ID | Ref | |
|---|---|---|---|---|---|
|
HHS-465 Probe Info |
 |
N.A. | LDD2240 | [1] | |