Details of the Target
General Information of Target
| Target ID | LDTP02414 | |||||
|---|---|---|---|---|---|---|
| Target Name | Serine protease 56 (PRSS56) | |||||
| Gene Name | PRSS56 | |||||
| Gene ID | 646960 | |||||
| Synonyms |
Serine protease 56; EC 3.4.21.- |
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| 3D Structure | ||||||
| Sequence |
MLLAVLLLLPLPSSWFAHGHPLYTRLPPSALQVLSAQGTQALQAAQRSAQWAINRVAMEI
QHRSHECRGSGRPRPQALLQDPPEPGPCGERRPSTANVTRAHGRIVGGSAAPPGAWPWLV RLQLGGQPLCGGVLVAASWVLTAAHCFVGAPNELLWTVTLAEGSRGEQAEEVPVNRILPH PKFDPRTFHNDLALVQLWTPVSPGGSARPVCLPQEPQEPPAGTACAIAGWGALFEDGPEA EAVREARVPLLSTDTCRRALGPGLRPSTMLCAGYLAGGVDSCQGDSGGPLTCSEPGPRPR EVLFGVTSWGDGCGEPGKPGVYTRVAVFKDWLQEQMSASSSREPSCRELLAWDPPQELQA DAARLCAFYARLCPGSQGACARLAHQQCLQRRRRCELRSLAHTLLGLLRNAQELLGPRPG LRRLAPALALPAPALRESPLHPARELRLHSGSRAAGTRFPKRRPEPRGEANGCPGLEPLR QKLAALQGAHAWILQVPSEHLAMNFHEVLADLGSKTLTGLFRAWVRAGLGGRHVAFSGLV GLEPATLARSLPRLLVQALQAFRVAALAEGEPEGPWMDVGQGPGLERKGHHPLNPQVPPA RQP |
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| Target Bioclass |
Enzyme
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| Family |
Peptidase S1 family
|
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| Function | Serine protease required during eye development. | |||||
| Uniprot ID | ||||||
| Ensemble ID | ||||||
| HGNC ID | ||||||
Probe(s) Labeling This Target
ABPP Probe
| Probe name | Structure | Binding Site(Ratio) | Interaction ID | Ref | |
|---|---|---|---|---|---|
|
DBIA Probe Info |
 |
C388(1.63); C256(1.56) | LDD3343 | [1] | |
|
IPM Probe Info |
 |
C388(0.00); C473(0.00); C366(0.00); C88(0.00) | LDD0147 | [2] | |
|
TFBX Probe Info |
 |
C373(0.00); C88(0.00); C388(0.00); C256(0.00) | LDD0148 | [2] | |
Competitor(s) Related to This Target
References