Details of the Target
General Information of Target
| Target ID | LDTP02393 | |||||
|---|---|---|---|---|---|---|
| Target Name | TCF3 fusion partner (TFPT) | |||||
| Gene Name | TFPT | |||||
| Gene ID | 29844 | |||||
| Synonyms |
INO80F; TCF3 fusion partner; INO80 complex subunit F; Protein FB1 |
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| 3D Structure | ||||||
| Sequence |
MELEQREGTMAAVGFEEFSAPPGSELALPPLFGGHILESELETEVEFVSGGLGGSGLRER
DEEEEAARGRRRRQRELNRRKYQALGRRCREIEQVNERVLNRLHQVQRITRRLQQERRFL MRVLDSYGDDYRASQFTIVLEDEGSQGTDAPTPGNAENEPPEKETLSPPRRTPAPPEPGS PAPGEGPSGRKRRRVPRDGRRAGNALTPELAPVQIKVEEDFGFEADEALDSSWVSRGPDK LLPYPTLASPASD |
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| Target Bioclass |
Other
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| Subcellular location |
Nucleus
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| Function |
Appears to promote apoptosis in a p53/TP53-independent manner.; Putative regulatory component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair.
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| Uniprot ID | ||||||
| Ensemble ID | ||||||
| HGNC ID | ||||||
Target Site Mutations in Different Cell Lines
Probe(s) Labeling This Target
ABPP Probe
| Probe name | Structure | Binding Site(Ratio) | Interaction ID | Ref | |
|---|---|---|---|---|---|
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JW-RF-010 Probe Info |
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N.A. | LDD0026 | [1] | |
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TFBX Probe Info |
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N.A. | LDD0027 | [1] | |
The Interaction Atlas With This Target
The Protein(s) Related To This Target
Enzyme
Other