Details of the Target
General Information of Target
| Target ID | LDTP02382 | |||||
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| Target Name | Intestinal-type alkaline phosphatase (ALPI) |
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| Gene Name | ALPI | |||||
| Gene ID | 248 | |||||
| Synonyms |
Intestinal-type alkaline phosphatase; IAP; Intestinal alkaline phosphatase; EC 3.1.3.1 |
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| 3D Structure | ||||||
| Sequence |
MQGPWVLLLLGLRLQLSLGVIPAEEENPAFWNRQAAEALDAAKKLQPIQKVAKNLILFLG
DGLGVPTVTATRILKGQKNGKLGPETPLAMDRFPYLALSKTYNVDRQVPDSAATATAYLC GVKANFQTIGLSAAARFNQCNTTRGNEVISVMNRAKQAGKSVGVVTTTRVQHASPAGTYA HTVNRNWYSDADMPASARQEGCQDIATQLISNMDIDVILGGGRKYMFPMGTPDPEYPADA SQNGIRLDGKNLVQEWLAKHQGAWYVWNRTELMQASLDQSVTHLMGLFEPGDTKYEIHRD PTLDPSLMEMTEAALRLLSRNPRGFYLFVEGGRIDHGHHEGVAYQALTEAVMFDDAIERA GQLTSEEDTLTLVTADHSHVFSFGGYTLRGSSIFGLAPSKAQDSKAYTSILYGNGPGYVF NSGVRPDVNESESGSPDYQQQAAVPLSSETHGGEDVAVFARGPQAHLVHGVQEQSFVAHV MAFAACLEPYTACDLAPPACTTDAAHPVAASLPLLAGTLLLLGASAAP |
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| Target Bioclass |
Enzyme
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| Family |
Alkaline phosphatase family
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| Subcellular location |
Cell membrane
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| Function | Alkaline phosphatase that can hydrolyze various phosphate compounds. | |||||
| Uniprot ID | ||||||
| Ensemble ID | ||||||
| HGNC ID | ||||||
| ChEMBL ID | ||||||
Probe(s) Labeling This Target
ABPP Probe
| Probe name | Structure | Binding Site(Ratio) | Interaction ID | Ref | |
|---|---|---|---|---|---|
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m-APA Probe Info |
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N.A. | LDD2231 | [1] | |