Details of the Target
General Information of Target
| Target ID | LDTP02190 | |||||
|---|---|---|---|---|---|---|
| Target Name | Histone H1.0 (H1-0) |
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| Gene Name | H1-0 | |||||
| Gene ID | 3005 | |||||
| Synonyms |
H1F0; H1FV; Histone H1.0; Histone H1'; Histone H1(0)) [Cleaved into: Histone H1.0, N-terminally processed] |
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| 3D Structure | ||||||
| Sequence |
MTENSTSAPAAKPKRAKASKKSTDHPKYSDMIVAAIQAEKNRAGSSRQSIQKYIKSHYKV
GENADSQIKLSIKRLVTTGVLKQTKGVGASGSFRLAKSDEPKKSVAFKKTKKEIKKVATP KKASKPKKAASKAPTKKPKATPVKKAKKKLAATPKKAKKPKTVKAKPVKASKPKKAKPVK PKAKSSAKRAGKKK |
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| Target Bioclass |
Other
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| Family |
Histone H1/H5 family
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| Subcellular location |
Nucleus
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| Function |
Histones H1 are necessary for the condensation of nucleosome chains into higher-order structures. The histones H1.0 are found in cells that are in terminal stages of differentiation or that have low rates of cell division.
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| Uniprot ID | ||||||
| Ensemble ID | ||||||
| HGNC ID | ||||||
| ChEMBL ID | ||||||
Probe(s) Labeling This Target
ABPP Probe
| Probe name | Structure | Binding Site(Ratio) | Interaction ID | Ref | |
|---|---|---|---|---|---|
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STPyne Probe Info |
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K121(10.00); K136(3.06); K144(10.00); K164(4.80) | LDD0277 | [1] | |
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NHS Probe Info |
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K69(0.00); K40(0.00); K82(0.00); K59(0.00) | LDD0010 | [2] | |
The Interaction Atlas With This Target
References