Details of the Target
General Information of Target
| Target ID | LDTP02134 | |||||
|---|---|---|---|---|---|---|
| Target Name | T-cell surface glycoprotein CD5 (CD5) |
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| Gene Name | CD5 | |||||
| Gene ID | 921 | |||||
| Synonyms |
LEU1; T-cell surface glycoprotein CD5; Lymphocyte antigen T1/Leu-1; CD antigen CD5 |
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| 3D Structure | ||||||
| Sequence |
MPMGSLQPLATLYLLGMLVASCLGRLSWYDPDFQARLTRSNSKCQGQLEVYLKDGWHMVC
SQSWGRSSKQWEDPSQASKVCQRLNCGVPLSLGPFLVTYTPQSSIICYGQLGSFSNCSHS RNDMCHSLGLTCLEPQKTTPPTTRPPPTTTPEPTAPPRLQLVAQSGGQHCAGVVEFYSGS LGGTISYEAQDKTQDLENFLCNNLQCGSFLKHLPETEAGRAQDPGEPREHQPLPIQWKIQ NSSCTSLEHCFRKIKPQKSGRVLALLCSGFQPKVQSRLVGGSSICEGTVEVRQGAQWAAL CDSSSARSSLRWEEVCREQQCGSVNSYRVLDAGDPTSRGLFCPHQKLSQCHELWERNSYC KKVFVTCQDPNPAGLAAGTVASIILALVLLVVLLVVCGPLAYKKLVKKFRQKKQRQWIGP TGMNQNMSFHRNHTATVRSHAENPTASHVDNEYSQPPRNSHLSAYPALEGALHRSSMQPD NSSDSDYDLHGAQRL |
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| Target Type |
Literature-reported
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| Target Bioclass |
Other
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| Subcellular location |
Cell membrane
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| Function | May act as a receptor in regulating T-cell proliferation. | |||||
| TTD ID | ||||||
| Uniprot ID | ||||||
| DrugMap ID | ||||||
| Ensemble ID | ||||||
| HGNC ID | ||||||
| ChEMBL ID | ||||||
Probe(s) Labeling This Target
ABPP Probe
| Probe name | Structure | Binding Site(Ratio) | Interaction ID | Ref | |
|---|---|---|---|---|---|
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TH211 Probe Info |
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Y453(20.00) | LDD0260 | [1] | |
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4-Iodoacetamidophenylacetylene Probe Info |
 |
C60(0.00); C321(0.00); C342(0.00); C285(0.00) | LDD0038 | [2] | |
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IA-alkyne Probe Info |
 |
C44(0.00); C60(0.00); C321(0.00); C342(0.00) | LDD0036 | [2] | |
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Lodoacetamide azide Probe Info |
 |
C44(0.00); C60(0.00); C321(0.00); C350(0.00) | LDD0037 | [2] | |
References