Details of the Target
General Information of Target
| Target ID | LDTP02133 | |||||
|---|---|---|---|---|---|---|
| Target Name | T-cell surface glycoprotein CD1a (CD1A) |
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| Gene Name | CD1A | |||||
| Gene ID | 909 | |||||
| Synonyms |
T-cell surface glycoprotein CD1a; T-cell surface antigen T6/Leu-6; hTa1 thymocyte antigen; CD antigen CD1a |
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| 3D Structure | ||||||
| Sequence |
MLFLLLPLLAVLPGDGNADGLKEPLSFHVTWIASFYNHSWKQNLVSGWLSDLQTHTWDSN
SSTIVFLCPWSRGNFSNEEWKELETLFRIRTIRSFEGIRRYAHELQFEYPFEIQVTGGCE LHSGKVSGSFLQLAYQGSDFVSFQNNSWLPYPVAGNMAKHFCKVLNQNQHENDITHNLLS DTCPRFILGLLDAGKAHLQRQVKPEAWLSHGPSPGPGHLQLVCHVSGFYPKPVWVMWMRG EQEQQGTQRGDILPSADGTWYLRATLEVAAGEAADLSCRVKHSSLEGQDIVLYWEHHSSV GFIILAVIVPLLLLIGLALWFRKRCFC |
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| Target Type |
Successful
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| Target Bioclass |
Immunoglobulin
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| Subcellular location |
Cell membrane
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| Function | Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells. | |||||
| TTD ID | ||||||
| Uniprot ID | ||||||
| DrugMap ID | ||||||
| Ensemble ID | ||||||
| HGNC ID | ||||||
Probe(s) Labeling This Target
ABPP Probe
| Probe name | Structure | Binding Site(Ratio) | Interaction ID | Ref | |
|---|---|---|---|---|---|
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4-Iodoacetamidophenylacetylene Probe Info |
 |
N.A. | LDD0038 | [1] | |
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IA-alkyne Probe Info |
 |
N.A. | LDD0166 | [2] | |
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Lodoacetamide azide Probe Info |
 |
C278(0.00); C119(0.00) | LDD0037 | [1] | |
The Interaction Atlas With This Target
References