General Information of Target

Target ID LDTP02049
Target Name Metallothionein-1A (MT1A)
Gene Name MT1A
Gene ID 4489
Synonyms
MT1S; Metallothionein-1A; MT-1A; Metallothionein-IA; MT-IA
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MDPNCSCATGGSCTCTGSCKCKECKCTSCKKSCCSCCPMSCAKCAQGCICKGASEKCSCC
A
Target Bioclass
Other
Family
Metallothionein superfamily, Type 1 family
Function Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids.
Uniprot ID
P04731
Ensemble ID
ENST00000290705.12
HGNC ID
HGNC:7393

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
4-Iodoacetamidophenylacetylene
 Probe Info 
N.A.  LDD0038  [1]

References

1 Enhancing Cysteine Chemoproteomic Coverage through Systematic Assessment of Click Chemistry Product Fragmentation. Anal Chem. 2022 Mar 8;94(9):3800-3810. doi: 10.1021/acs.analchem.1c04402. Epub 2022 Feb 23.
Mass spectrometry data entry: PXD028853