Details of the Target
General Information of Target
| Target ID | LDTP02017 | |||||
|---|---|---|---|---|---|---|
| Target Name | Trefoil factor 1 (TFF1) |
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| Gene Name | TFF1 | |||||
| Gene ID | 7031 | |||||
| Synonyms |
BCEI; PS2; Trefoil factor 1; Breast cancer estrogen-inducible protein; PNR-2; Polypeptide P1.A; hP1.A; Protein pS2 |
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| 3D Structure | ||||||
| Sequence |
MATMENKVICALVLVSMLALGTLAEAQTETCTVAPRERQNCGFPGVTPSQCANKGCCFDD
TVRGVPWCFYPNTIDVPPEEECEF |
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| Target Type |
Clinical trial
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| Target Bioclass |
Other
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| Subcellular location |
Secreted
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| Function | Stabilizer of the mucous gel overlying the gastrointestinal mucosa that provides a physical barrier against various noxious agents. May inhibit the growth of calcium oxalate crystals in urine. | |||||
| TTD ID | ||||||
| Uniprot ID | ||||||
| DrugMap ID | ||||||
| Ensemble ID | ||||||
| HGNC ID | ||||||
Probe(s) Labeling This Target
ABPP Probe
| Probe name | Structure | Binding Site(Ratio) | Interaction ID | Ref | |
|---|---|---|---|---|---|
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NAIA_5 Probe Info |
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C57(0.00); C56(0.00) | LDD2223 | [1] | |