General Information of Target

Target ID LDTP01921
Target Name Hemoglobin subunit delta (HBD)
Gene Name HBD
Gene ID 3045
Synonyms
Hemoglobin subunit delta; Delta-globin; Hemoglobin delta chain
3D Structure
Download
2D Sequence (FASTA)
Download
3D Structure (PDB)
Download
Sequence
MVHLTPEEKTAVNALWGKVNVDAVGGEALGRLLVVYPWTQRFFESFGDLSSPDAVMGNPK
VKAHGKKVLGAFSDGLAHLDNLKGTFSQLSELHCDKLHVDPENFRLLGNVLVCVLARNFG
KEFTPQMQAAYQKVVAGVANALAHKYH
Target Bioclass
Other
Family
Globin family
Function Involved in oxygen transport from the lung to the various peripheral tissues.
Uniprot ID
P02042
Ensemble ID
ENST00000643122.1
HGNC ID
HGNC:4829

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info 
C94(1.76)  LDD2324  [1]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0022  KB02 EoL-1 C94(1.76)  LDD2324  [1]
 LDCM0023  KB03 EoL-1 C94(1.97)  LDD2741  [1]
 LDCM0024  KB05 EoL-1 C94(1.89)  LDD3158  [1]

References

1 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840