Details of the Target
General Information of Target
| Target ID | LDTP01654 | |||||
|---|---|---|---|---|---|---|
| Target Name | Amyloid-beta A4 precursor protein-binding family B member 3 (APBB3) | |||||
| Gene Name | APBB3 | |||||
| Gene ID | 10307 | |||||
| Synonyms |
FE65L2; Amyloid-beta A4 precursor protein-binding family B member 3; Protein Fe65-like 2; Fe65L2 |
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| 3D Structure | ||||||
| Sequence |
MLGKDYMLAIILVNCDDDLWGDHSLEVEAGLPPGWRKIHDAAGTYYWHVPSGSTQWQRPT
WELGDAEDPGTGTEGIWGLRPPKGRSFSSLESSLDRSNSLSWYGGESYIQSMEPGAKCFA VRSLGWVEVPEEDLAPGKSSIAVNNCIQQLAQTRSRSQPPDGAWGEGQNMLMILKKDAMS LVNPLDHSLIHCQPLVHIRVWGVGSSKGRDRDFAFVASDKDSCMLKCHVFCCDVPAKAIA SALHGLCAQILSERVEVSGDASCCSPDPISPEDLPRQVELLDAVSQAAQKYEALYMGTLP VTKAMGMDVLNEAIGTLTARGDRNAWVPTMLSVSDSLMTAHPIQAEASTEEEPLWQCPVR LVTFIGVGRDPHTFGLIADLGRQSFQCAAFWCQPHAGGLSEAVQAACMVQYQKCLVASAA RGKAWGAQARARLRLKRTSSMDSPGGPLPLPLLKGGVGGAGATPRKRGVFSFLDAFRLKP SLLHMP |
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| Target Bioclass |
Other
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| Subcellular location |
Cytoplasm; Nucleus
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| Function | May modulate the internalization of amyloid-beta precursor protein. | |||||
| Uniprot ID | ||||||
| Ensemble ID | ||||||
| HGNC ID | ||||||
Probe(s) Labeling This Target
ABPP Probe
| Probe name | Structure | Binding Site(Ratio) | Interaction ID | Ref | |
|---|---|---|---|---|---|
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IA-alkyne Probe Info |
 |
N.A. | LDD2241 | [1] | |